| A longitudinal analysis of the relations among stress, depressive symptoms, leisure satisfaction, and endothelial function in caregivers. | |
| | |
MedLine Citation:
|
PMID: 22486550 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Stress and depressive symptoms have been associated with impaired endothelial function as measured by brachial artery flow-mediated dilation (FMD), possibly through repeated and heightened activation of the sympathetic nervous system. Behavioral correlates of depression, such as satisfaction with leisure activities (i.e., leisure satisfaction), may also be associated with endothelial function via their association with depressive symptoms. This study examined the longitudinal associations between stress, depressive symptoms, leisure satisfaction, and endothelial function as measured by FMD. METHOD: Participants were 116 older Alzheimer's caregivers (M age = 74.3 ± 8.1; 68% women; 87% white) who underwent 3 yearly assessments of FMD, stress, depressive symptoms, and leisure satisfaction. Mixed-regression analyses were used to examine longitudinal relationships between constructs of interest. RESULTS: A significant and positive association was found between leisure satisfaction and FMD (p = .050), whereas a negative relationship was found for stress (p = .017). Depressive symptoms were not associated with FMD (p = .432). Time (p < .001) and the number of years caregiving (p = .027) were also significant predictors of FMD, suggesting that FMD decreased over time and was worse the longer a participant had been a caregiver prior to study enrollment. CONCLUSIONS: These results suggest that behavioral correlates of depression (i.e., engagement in pleasurable activities) may be related to endothelial function in caregivers, and behavioral treatments for depression may be particularly useful in improving cardiovascular outcomes in caregivers. |
| | |
Authors:
|
Brent T Mausbach; Elizabeth Chattillion; Susan K Roepke; Michael G Ziegler; Milos Milic; Roland von Känel; Joel E Dimsdale; Paul J Mills; Thomas L Patterson; Matthew A Allison; Sonia Ancoli-Israel; Igor Grant |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural Date: 2012-04-09 |
Journal Detail:
|
Title: Health psychology : official journal of the Division of Health Psychology, American Psychological Association Volume: 31 ISSN: 1930-7810 ISO Abbreviation: Health Psychol Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-07-10 Completed Date: 2012-10-19 Revised Date: 2013-04-16 |
Medline Journal Info:
|
Nlm Unique ID: 8211523 Medline TA: Health Psychol Country: United States |
Other Details:
|
Languages: eng Pagination: 433-40 Citation Subset: IM |
Affiliation:
|
Department of Psychiatry, University of California San Diego, La Jolla 92093-0680, USA. bmausbach@ucsd.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Alzheimer Disease / nursing Brachial Artery / physiopathology Caregivers / psychology* Depression / physiopathology* Endothelium, Vascular / physiopathology European Continental Ancestry Group Female Humans Leisure Activities Longitudinal Studies Male Personal Satisfaction Regression Analysis Stress, Psychological* |
| Grant Support | |
ID/Acronym/Agency:
|
AG 03090/AG/NIA NIH HHS; AG 15301/AG/NIA NIH HHS; R01 AG031090/AG/NIA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Health Care Utilization and Psychosocial Factors in Pediatric Noncardiac Chest Pain.
Next Document: Novel immunomic technologies for schistosome vaccine development.