Document Detail

Longissimus muscle and plasma enzymes and metabolites in fetally decapitated pigs.
MedLine Citation:
PMID:  750309     Owner:  NLM     Status:  MEDLINE    
Fetuses of nine gilts were decapitated (D) in utero and fetuses of eight gilts were sham operated (C) at 43 to 47 days of pregnancy. At 110 days, one fetus from each gilt was studied. Heart, liver, kidney, thyroid and body weights were recorded. Thyroids were evaluated for the degree of colloid accumulation and height of the follicular epithelium. Blood glucose, lactate, triglycerides and creatine phosphokinase activity were determined. Longissimus muscle glycogen was evaluated histochemically. Longissimus muscle total phosphorylase, phosphorylase a, G-6-PDH and SDH activity and glycogen were determined biochemically. The D fetuses were hairless, edematous, devoid of adrenal glands and unaffected by maternal anesthesia. Results indicate that the fetal pig pituitary gland is not required for continued fetal growth, but is necessary for normal organ and endocrine gland development. Fetal decapitation caused delayed maturation of the longissimus muscle with little change in anaerobic glycolytic capacity but decreased aerobic glycolytic capacity accompanied by increased activity of the pentose shunt.
R R Kraeling; G B Rampacek; D R Campion; R L Richardson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Growth     Volume:  42     ISSN:  0017-4793     ISO Abbreviation:  Growth     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-07-25     Completed Date:  1979-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0205044     Medline TA:  Growth     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  457-68     Citation Subset:  IM    
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MeSH Terms
Blood Glucose
Body Weight
Creatine Kinase / blood
Fetus / metabolism*
Glucosephosphate Dehydrogenase / analysis
Glycogen / analysis
Lactates / blood
Muscle Proteins / analysis
Muscles / analysis,  enzymology*
Organ Size
Phosphorylases / analysis
Succinate Dehydrogenase / analysis
Swine / metabolism*
Triglycerides / blood
Reg. No./Substance:
0/Blood Glucose; 0/Lactates; 0/Muscle Proteins; 0/Triglycerides; 9005-79-2/Glycogen; EC Dehydrogenase; EC Dehydrogenase; EC 2.4.1.-/Phosphorylases; EC Kinase

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