Document Detail

Long term treatment of myasthenia gravis with azathioprine.
MedLine Citation:
PMID:  2112245     Owner:  NLM     Status:  MEDLINE    
Twenty-seven patients with myasthenia gravis have been treated with azathioprine in conjunction with pyridostigmine and prednisolone for a total of 138 patient years. Side effects necessitated discontinuation of treatment in only four patients. Treatment with azathioprine was associated with marked clinical improvement in all the remaining 23 patients, resulting in reduction in the dose of pyridostigmine and prednisolone. The number of hospital admissions as well as the number of episodes of respiratory failure were markedly reduced.
V Fonseca; C W Havard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  66     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-07-09     Completed Date:  1990-07-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  102-5     Citation Subset:  IM    
Royal Free Hospital, London, UK.
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MeSH Terms
Azathioprine / adverse effects,  therapeutic use*
Drug Therapy, Combination
Hypertension, Portal / chemically induced
Jaundice / chemically induced
Long-Term Care
Middle Aged
Myasthenia Gravis / drug therapy*
Prednisolone / therapeutic use
Pyridostigmine Bromide / therapeutic use
Reg. No./Substance:
101-26-8/Pyridostigmine Bromide; 446-86-6/Azathioprine; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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