Document Detail

Long-term treatment of duodenal ulcer.
MedLine Citation:
PMID:  6328683     Owner:  NLM     Status:  MEDLINE    
Eighty per cent or more of duodenal and gastric ulcers which have healed after a course of treatment with drugs relapse when therapy is discontinued. Only a gastric operation or continuous maintenance treatment with H2-receptor antagonists has so far been shown to produce sustained remission in the majority of patients. Maintenance treatment with drugs is safer than gastric surgery, since the adverse effects of medical therapy are uncommon, mild and reversible while the after-effects of surgery are common and may be severe and irreversible. Ranitidine is preferred to cimetidine because it has no unwanted effects. The maintenance treatment of ulcer patients with ranitidine must be continued for many years and may have to be life-long.
K G Wormsley
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  65     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-07-17     Completed Date:  1984-07-17     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  1001-4     Citation Subset:  IM    
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MeSH Terms
Cimetidine / administration & dosage
Costs and Cost Analysis
Duodenal Ulcer / economics,  mortality,  surgery,  therapy*
Postoperative Complications
Ranitidine / administration & dosage
Stomach Neoplasms / complications
Stomach Ulcer / mortality,  surgery,  therapy
Reg. No./Substance:
80061L1WGD/Cimetidine; 884KT10YB7/Ranitidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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