Document Detail


Long-term survival and serial assessment of stroke damage and recovery - practical and methodological considerations.
MedLine Citation:
PMID:  22389748     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Impairments caused by stroke remain the main cause for adult disability. Despite a vigorous research effort, only 1 thrombolytic treatment has been approved in acute stroke (<3h). The limitations of preclinical studies and how these can be overcome have been the subject of various guidelines. However, often these guidelines focus on the acute stroke setting and omit long-term outcome measures, such as behaviour and neuroimaging. The considerations and practicalities of including the serial assessment of these approaches and their significance to establish therapeutic efficacy are discussed here.
Authors:
Michel Modo
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of experimental stroke & translational medicine     Volume:  2     ISSN:  1939-067X     ISO Abbreviation:  -     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2012-3-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101514232     Medline TA:  J Exp Stroke Transl Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  52-68     Citation Subset:  -    
Affiliation:
King's College London, Institute of Psychiatry, Department of Neuroscience, London, UK.
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Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
P20 EB007076-01//NIBIB NIH HHS

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