| Long-term survival in a patient with acute promyelocytic leukemia with isolated meningeal relapse. | |
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MedLine Citation:
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PMID: 21120212 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The meningeal involvement is rare in acute promyelocytic leukemia. We experienced a 39-year-old woman who achieved complete remission with all-trans retinoic acid, idarubicin and cytarabine therapy. Several months later, she complained of non-specific headache. Her complete blood cell count was normal, but magnetic resonance image of brain revealed focal meningeal enhancement and cerebrospinal fluid showed leukemic promyelocytes and PML/RARA rearrangement. Bone marrow study showed hematologic, cytogenetic and molecular remission. She was treated with intrathecal and systemic chemotherapy and whole brain radiotherapy. The patient has survived for 68 months since the last systemic chemotherapy. |
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Authors:
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Se Hyung Kim; Jina Yun; Hyun Jung Kim; Chan Kyu Kim; Sung Kyu Park; Dae Sik Hong |
Publication Detail:
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Type: Journal Article Date: 2010-09-30 |
Journal Detail:
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Title: The Korean journal of hematology Volume: 45 ISSN: 2092-9129 ISO Abbreviation: Korean J Hematol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101486388 Medline TA: Korean J Hematol Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 208-10 Citation Subset: - |
Affiliation:
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Department of Hematology-Oncology, Soonchunhyang University College of Medicine, Bucheon, Korea. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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