Document Detail

Long-term survival after a massive left ventricular infarction evidenced by FDG-PET and leaving intact only the septal wall.
MedLine Citation:
PMID:  23236563     Owner:  NLM     Status:  PubMed-not-MEDLINE    
There is evidence that survival remains possible for infarction greater than 50% of the left ventricle in human, as well as in the rat infarct model. To our knowledge, survival has not been documented for infarctions involving the anterior, inferior and lateral wall leaving intact only the septal wall. An adult rat underwent a ligation of the left anterior descending coronary artery. ECG-triggered (18)F-ffluorodeoxyglucose Positron Emission Tomography revealed that 72% of the left ventricle was necrotic and totally akinetic. Although the left ventricular ejection fraction was severely impaired (9%), this rat survived and was asymptomatic after 2 months. The exact reasons for this incredible survival are still unclear.
Mélanie Bousquenaud; Daniel R Wagner; Fathia Maskali; Pierre-Yves Marie; Yvan Devaux
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Publication Detail:
Type:  Journal Article     Date:  2012-11-18
Journal Detail:
Title:  International journal of clinical and experimental medicine     Volume:  6     ISSN:  1940-5901     ISO Abbreviation:  Int J Clin Exp Med     Publication Date:  2013  
Date Detail:
Created Date:  2012-12-13     Completed Date:  2012-12-14     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101471010     Medline TA:  Int J Clin Exp Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-5     Citation Subset:  -    
Laboratory of Cardiovascular Research, Centre de Recherche Public-Santé Luxembourg.
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