Document Detail


Long-term results of nephron-sparing surgery for renal cell carcinoma in 114 patients: risk factors for progressive disease.
MedLine Citation:
PMID:  14511035     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To evaluate risk factors for metastatic disease after nephron-sparing surgery (NSS) for renal cell carcinoma (RCC). PATIENTS AND METHODS: NSS for RCC was used 117 times in 114 patients at our institution; 61 had a normal contralateral kidney and were selected for elective NSS, and in 56 cases (53 patients) the indication for NSS was imperative. Univariate and multiple regression analysis was used to evaluate the risk factors for metastatic disease. RESULTS: After a mean follow-up of 80 months, there was tumour progression in 17 of the 114 patients (15%). In the univariate analysis, the tumour diameter (P = 0.03) and imperative indication (P = 0.009), and in multiple regression analysis only imperative indication, were significant risk factors for metastatic disease (P = 0.016). CONCLUSIONS: Elective NSS for RCC provides excellent long-term results in selected patients, whereas those undergoing NSS imperatively are at a significantly higher risk of metastatic disease and require a close follow-up.
Authors:
R Zigeuner; F Quehenberger; K Pummer; P Petritsch; G Hubmer
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  BJU international     Volume:  92     ISSN:  1464-4096     ISO Abbreviation:  BJU Int.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-09-26     Completed Date:  2003-10-30     Revised Date:  2006-07-18    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  567-71     Citation Subset:  IM    
Affiliation:
Department of Urology, University Hospital of Graz, Karl-Franzens University Graz, Graz, Austria. richard.zigeuner@kfunigraz.ac.at
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Analysis of Variance
Carcinoma, Renal Cell / surgery*
Disease-Free Survival
Female
Follow-Up Studies
Humans
Kidney Neoplasms / surgery*
Male
Middle Aged
Nephrectomy / methods*
Nephrons / surgery*
Postoperative Complications / etiology*
Risk Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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