| Long-term results of nephron-sparing surgery for renal cell carcinoma in 114 patients: risk factors for progressive disease. | |
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MedLine Citation:
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PMID: 14511035 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To evaluate risk factors for metastatic disease after nephron-sparing surgery (NSS) for renal cell carcinoma (RCC). PATIENTS AND METHODS: NSS for RCC was used 117 times in 114 patients at our institution; 61 had a normal contralateral kidney and were selected for elective NSS, and in 56 cases (53 patients) the indication for NSS was imperative. Univariate and multiple regression analysis was used to evaluate the risk factors for metastatic disease. RESULTS: After a mean follow-up of 80 months, there was tumour progression in 17 of the 114 patients (15%). In the univariate analysis, the tumour diameter (P = 0.03) and imperative indication (P = 0.009), and in multiple regression analysis only imperative indication, were significant risk factors for metastatic disease (P = 0.016). CONCLUSIONS: Elective NSS for RCC provides excellent long-term results in selected patients, whereas those undergoing NSS imperatively are at a significantly higher risk of metastatic disease and require a close follow-up. |
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Authors:
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R Zigeuner; F Quehenberger; K Pummer; P Petritsch; G Hubmer |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: BJU international Volume: 92 ISSN: 1464-4096 ISO Abbreviation: BJU Int. Publication Date: 2003 Oct |
Date Detail:
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Created Date: 2003-09-26 Completed Date: 2003-10-30 Revised Date: 2006-07-18 |
Medline Journal Info:
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Nlm Unique ID: 100886721 Medline TA: BJU Int Country: England |
Other Details:
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Languages: eng Pagination: 567-71 Citation Subset: IM |
Affiliation:
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Department of Urology, University Hospital of Graz, Karl-Franzens University Graz, Graz, Austria. richard.zigeuner@kfunigraz.ac.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Analysis of Variance Carcinoma, Renal Cell / surgery* Disease-Free Survival Female Follow-Up Studies Humans Kidney Neoplasms / surgery* Male Middle Aged Nephrectomy / methods* Nephrons / surgery* Postoperative Complications / etiology* Risk Factors Treatment Outcome |
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