Document Detail

Long term results of lateral pancreaticojejunostomy for chronic alcoholic pancreatitis.
MedLine Citation:
PMID:  10688219     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess our long term results of lateral pancreaticojejunostomy in patients with alcoholic pancreatitis. DESIGN: Retrospective study. SETTING: University hospital, France. SUBJECTS: 57 patients (48 men, 9 women, mean (SD) age 46 (7) years who required surgical treatment of chronic alcoholic pancreatitis between January 1977 and October 1995. INTERVENTIONS: Lateral pancreaticojejunostomy with or without another procedure. Outcome classified as excellent, good, fair, or poor. MAIN OUTCOME MEASURES: Postoperative morbidity and mortality; relief of pain; reduction in use of analgesics and exocrine supplements; effect on exocrine and endocrine insufficiency; and return to paid work. RESULTS: There were no postoperative deaths and no pancreatic fistulae, but there were 17 other postoperative complications (30%). Median follow up was 65 months (range 8-206), during which 12 patients died (21%). Result was judged excellent in 16 (28%), good in 27 (47%), fair in 5 (9%), and poor in 9 (16%). Pain control was significantly improved, analgesic usage decreased, less pancreatic enzyme supplementation was required, and 25 patients returned to paid work (p = 0.0001 in each case). Exocrine and endocrine function remained stable. The results were better if the patient gave up misusing alcohol (p = 0.03) and if the operation was done within 4 years of the development of pancreatitis (p = 0.03). CONCLUSIONS: Lateral pancreaticojejunostomy is a safe procedure that can improve functional outcome in patients with chronic alcoholic pancreatitis, and does not worsen pancreatic function.
I Sielezneff; A Malouf; E Salle; C Brunet; X Thirion; B Sastre
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The European journal of surgery = Acta chirurgica     Volume:  166     ISSN:  1102-4151     ISO Abbreviation:  Eur J Surg     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-04-05     Completed Date:  2000-04-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9105264     Medline TA:  Eur J Surg     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  58-64     Citation Subset:  IM    
Department of Digestive Surgery, Hôpital Sainte-Marguerite, Marseille, France.
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MeSH Terms
Chronic Disease
Follow-Up Studies
Islets of Langerhans / physiopathology
Middle Aged
Pancreas / physiopathology
Pancreatitis, Alcoholic / physiopathology,  rehabilitation,  surgery*
Retrospective Studies
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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