Document Detail


Long-term results in the elderly following pulmonary resection for non-small cell lung carcinoma.
MedLine Citation:
PMID:  8129959     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The long-term results of 647 patients undergoing pulmonary resection for non-small cell lung carcinoma (NSCLC) between 1980-1988 were reviewed. One hundred forty-five (22%) were elderly patients (70 years or more, group 1), with a mean age of 72.3 years (70-81) and the other 502 (18%) were younger (69 years or less, group 2) with a mean age of 61.4 (40-69) years. The male to female ratio was 4:1 in group 1 and 3:1 in group 2. The number of patients in group 2 (n = 234, 47%) who underwent pneumonectomy was significantly greater (P < 0.01), compared to group 1 (n = 47, 32%). Cardiopulmonary complications were more frequently observed in group 1 (19.3%) than in group 2 (7.4%), P < 0.05. Although cardiac complications (i.e. arrhythmias) were more common in the elderly group, pulmonary complications (retained secretions, atelectasis) occurred more commonly in the younger group. The overall hospital mortality in group 1 and group 2 was 8.9% and 5.3%, respectively (NS), and mortality following pneumonectomy in group 1 (10.6%) was similar to that of group 2 (7.6%) (NS). The 2- and 5-year overall actuarial survival rates were 61% and 30% in group 1 and 57% and 37% in group 2 (NS). Superior survival was achieved in patients in stage I of the disease in both groups. Cell type was not a determinant of long-term survival differences between the groups whereas type of operation (lobectomy) and sex (female) were.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
C Gebitekin; N K Gupta; P G Martin; N R Saunders; D R Walker
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  7     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  1993  
Date Detail:
Created Date:  1994-04-21     Completed Date:  1994-04-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  653-6     Citation Subset:  IM    
Affiliation:
Cardiothoracic Surgery Unit, Killingbeck Hospital, Leeds, UK.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / mortality,  pathology,  surgery*
Adult
Age Factors
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung / mortality,  pathology,  surgery*
Carcinoma, Squamous Cell / mortality,  pathology,  surgery*
Combined Modality Therapy
Female
Hospital Mortality
Humans
Lung Neoplasms / mortality,  pathology,  surgery*
Male
Middle Aged
Neoplasm Staging
Pneumonectomy*
Postoperative Care
Postoperative Complications / epidemiology
Sex Factors
Survival Rate
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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