Document Detail

Long-term results of complete and partial ligation of congenital portosystemic shunts in dogs.
MedLine Citation:
PMID:  7571385     Owner:  NLM     Status:  MEDLINE    
The medical records of 65 dogs that underwent complete or partial ligation of a single congenital portosystemic shunt (CPSS) were reviewed to determine the long-term clinical clinical results. Information retrieved from the records included age at surgery, preligation (baseline) portal pressure, postligation portal pressure, change in portal pressure from baseline, complete or partial occlusion of the shunting vessel and fasting, and 2-hour postprandial bile acids from the preoperative, early postoperative (PO), and greater than 1 year PO time periods. A clinical rating score derived from a follow-up examination greater than 1 year PO was assigned to each dog. Of the 56 dogs that survived the perioperative period, 29 (52%) had complete and 27 (48%) had partial ligations. Age at surgery, pre- and postligation portal pressure, change in portal pressure from baseline and serum bile acid concentrations were not related to long-term clinical outcome. Clinical rating scores were significantly greater for dogs with partial CPSS ligations compared with dogs with complete ligations, indicating a less favorable clinical outcome for partial ligations. Fasting and 2-hour postprandial bile acid values at both PO time intervals were significantly greater in partial versus complete ligation groups. Follow-up information for more than 1 year was available on 18 of 29 dogs (62%) with complete ligations. All were clinically normal. Of 27 dogs with partial ligations, 11 dogs (41%) developed recurrence of clinical signs resulting in presentation to the university or referring veterinarian for additional surgery, medical management, or euthanasia. Only three dogs with partial CPSS ligation (11%) were clinically normal.(ABSTRACT TRUNCATED AT 250 WORDS)
H A Hottinger; R Walshaw; J G Hauptman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Veterinary surgery : VS     Volume:  24     ISSN:  0161-3499     ISO Abbreviation:  Vet Surg     Publication Date:    1995 Jul-Aug
Date Detail:
Created Date:  1995-11-21     Completed Date:  1995-11-21     Revised Date:  2011-04-25    
Medline Journal Info:
Nlm Unique ID:  8113214     Medline TA:  Vet Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  331-6     Citation Subset:  IM    
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, USA.
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MeSH Terms
Bile Acids and Salts / analysis
Dog Diseases / congenital,  physiopathology,  surgery*
Ligation / veterinary
Longitudinal Studies
Portal Pressure / physiology
Portal System / abnormalities*,  surgery
Retrospective Studies
Reg. No./Substance:
0/Bile Acids and Salts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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