Document Detail

Long-term results of bioprosthetic mitral valve replacement: the pericardial perspective.
MedLine Citation:
PMID:  15736567     Owner:  NLM     Status:  MEDLINE    
Pericardial valve bioprostheses were introduced in early 1970s and were widely used in the 1980s. The longterm results with the Ionescu-Shiley valve, the first commercially available pericardial valve, were disappointing because of high rate cusp tears during the first decade after implantation. The enthusiasm for this type of bioprosthetic valve was further hampered by the premature failure of the Hancock pericardial valve. The long-term results of aortic valve replacement with the Carpentier-Edwards pericardial valve, which was introduced in 1981, indicated that that valve was durable and the issue of cusp tears had been resolved by an appropriate design. This knowledge prompted surgeons to revisit the merits of pericardial valves for mitral valve replacement and several other pericardial valves are now commercially available. The largest data on long-term results are with the Carpentier-Edwards pericardial mitral valve. The reported freedom from structure valve failure ranged from 69% to 85% at 10 years in patient population with mean age of 60 to 70 years. Young age is a major determinant of valve failure, which is largely due to calcification. There are also long-term data, albeit more limited on the Sorin Pericarbon and Mitroflow valves used for mitral valve replacement. This paper review the published experience with various pericardial bioprosthetic valves used for mitral valve replacement during the past 3 decades.
T Doenst; M A Borger; T E David
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  45     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2005-03-01     Completed Date:  2005-03-22     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  449-54     Citation Subset:  IM    
Division of Cardiovascular Surgery, Toronto General Hospital and University of Toronto Toronto, Ontario, Canada.
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MeSH Terms
Echocardiography, Doppler
Follow-Up Studies
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / adverse effects,  methods*
Middle Aged
Mitral Valve Insufficiency / surgery*,  ultrasonography
Mitral Valve Stenosis / surgery*,  ultrasonography
Prosthesis Design
Prosthesis Failure
Risk Assessment
Severity of Illness Index
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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