Document Detail


Long-term results of antireflux surgery indicate the need for a randomized clinical trial.
MedLine Citation:
PMID:  11856139     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Well conducted, comparative trials of laparoscopic versus open antireflux surgery with an adequate patient enrollment are few and they do not demonstrate obvious advantages for the laparoscopic approach except for a marginal gain in shorter hospital stay. The aim of this study was to compare the effectiveness of laparoscopic and open procedures. METHODS: Two unselected groups of 230 patients were identified through a register of all inpatient public care in Sweden. Outcomes of laparoscopic and open antireflux surgery were compared using a disease-specific questionnaire 4 years after operation. RESULTS: Failure and dissatisfaction were significantly more common in the laparoscopy group than among patients having conventional open surgery. Treatment failure rates were 29.0 and 14.6 per cent respectively (P = 0.004). Dissatisfaction rates were 15.0 and 7.0 per cent respectively (P = 0.005). There was no other questionnaire item for which the proportion of failures differed significantly between the two groups. CONCLUSION: This study does not support the presumption that laparoscopic antireflux surgery is to be preferred to the open procedure. It is strongly recommended that a randomized controlled trial be conducted.
Authors:
R Sandbu; H Khamis; S Gustavsson; U Haglund
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  89     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-21     Completed Date:  2002-03-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  225-30     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Uppsala University, Uppsala, Sweden. rune.sandbu@zeta.telenordia.se
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Body Mass Index
Cicatrix
Deglutition Disorders / etiology
Female
Flatulence / etiology
Gases
Gastroesophageal Reflux / epidemiology,  surgery*
Humans
Laparoscopy / adverse effects,  methods,  standards*
Laparotomy / adverse effects,  methods,  standards*
Male
Middle Aged
Patient Satisfaction
Questionnaires
Randomized Controlled Trials as Topic
Sex Factors
Sweden / epidemiology
Treatment Outcome
Chemical
Reg. No./Substance:
0/Gases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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