Document Detail


Long-term results after successful percutaneous transluminal coronary angioplasty in patients over 75 years of age.
MedLine Citation:
PMID:  8651118     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective study comparing the long-term results of balloon angioplasty in patients over 75 years of age with those in a younger patient group is not available. A total of 192 consecutive patients aged > or = 75 years (group I) who underwent a balloon angioplasty were matched with 192 control patients aged 40 to 65 years (group II). The groups were matched for gender, angina pectoris class, left ventricular function, 1-, 2-, and 3-vessel coronary artery disease, and previous myocardial infarction. The mean follow-up was 40.4 months (range 0 to 110). Actuarial analysis (freedom from events) after 5 years yielded the following results for group I versus group II: free from death remained 77.1% versus 97.9% (p = 0.0001), from cardiac death 92.4% versus 97.9% (p = 0.049), and from angina pectoris 54.6% versus 75.1% (p = 0.03). The differences were not significant for those remaining free from myocardial infarction, repeat balloon angioplasty, or coronary artery bypass grafting. When elderly patients with complete revascularization (n = 127) were compared with a matched control group of 127 patients aged 40 to 65 years who underwent complete revascularization, there was only a significant difference in noncardiac death rates. We conclude that patients > 75 years of age have a significant higher cardiac and noncardiac death rate and a higher incidence of angina pectoris after successful balloon angioplasty. However, the incidence of reintervention and myocardial infarction is lower in the elderly. If complete revascularization is achieved in the elderly, then freedom from cardiac death and recurrence of angina pectoris would be comparable to that in younger patients.
Authors:
J M ten Berg; A A Voors; M J Suttorp; S M Ernst; E G Mast; E Bal; H W Plokker
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  77     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-07-25     Completed Date:  1996-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  690-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Actuarial Analysis
Adult
Aged
Aged, 80 and over
Aging*
Angina Pectoris / therapy
Angioplasty, Transluminal, Percutaneous Coronary*
Case-Control Studies
Coronary Artery Bypass
Coronary Disease / pathology,  surgery,  therapy
Death, Sudden, Cardiac / etiology
Disease-Free Survival
Female
Follow-Up Studies
Humans
Longitudinal Studies
Male
Middle Aged
Myocardial Infarction / pathology,  therapy
Prospective Studies
Survival Rate
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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