Document Detail

Long-term results of Malone's procedure with antegrade irrigation for severe chronic constipation.
MedLine Citation:
PMID:  20299171     Owner:  NLM     Status:  MEDLINE    
AIM: The Malone antegrade colonic enema (MACE) procedure is a minimally invasive treatment for severe constipation, and the objective of the present study was to assess the long-term results and quality of life in patients undergoing such colonic irrigation. METHOD: Twenty-five adult patients underwent MACE between 1995 and 2002 for chronic constipation. After a mean follow-up duration of 55+/-36 months, the patients answered questionnaires to assess stoma usage, constipation score (KESS) and quality of life (GIQLI). RESULTS: The mean quality-of-life scores for these patients was 83+/-28 (normal: 125), while their mean constipation score was 19+/-9 (normal: <7). Twelve patients stopped the irrigations, and eight underwent further surgical procedures, specifically, total colectomy with ileostomy (n=2), ileorectal anastomosis (n=3) or segmental colectomy (n=3). Finally, five patients had permanent stoma. The 13 remaining patients continued to perform irrigations (4.6 per week). The patients' mean KESS score was 18.3+/-8 (normal: <7), and the mean GIQLI score was 98+/-20 (normal: 125). Continence status had no influence on success. CONCLUSION: In our series, MACE was successful in half the patients who were, thus, able to avoid more aggressive approaches. However, when MACE failed, other surgical procedures were often required.
G Meurette; P-A Lehur; E Coron; N Regenet
Publication Detail:
Type:  Journal Article     Date:  2010-03-17
Journal Detail:
Title:  Gastroentérologie clinique et biologique     Volume:  34     ISSN:  2210-7401     ISO Abbreviation:  Gastroenterol. Clin. Biol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-05     Completed Date:  2010-07-23     Revised Date:  2010-08-17    
Medline Journal Info:
Nlm Unique ID:  7704825     Medline TA:  Gastroenterol Clin Biol     Country:  France    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  IM    
Institut des maladies de l'appareil digestif, Hôtel-Dieu-CHU de Nantes, 1, place Alexis-Ricordeau, 44035 Nantes cedex, France. <>
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anastomosis, Surgical
Chronic Disease
Colectomy / methods*
Constipation / surgery*,  therapy
Enema / methods*
Follow-Up Studies
Ileostomy / methods
Ileum / surgery
Middle Aged
Quality of Life*
Rectum / surgery
Retrospective Studies
Severity of Illness Index
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Interstitial pneumonia related to mesalamine.
Next Document:  Technical aspects of MR diffusion imaging of the body.