| Long-term remission of refractory stiff-man syndrome after treatment with intravenous immunoglobulin. | |
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MedLine Citation:
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PMID: 10593352 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The stiff-man syndrome is a rare neuromuscular disorder characterized by progressive rigidity, stiffness, and intermittent spasm of axial and extremity muscles. Its etiology is unknown. Different therapeutic regimens have been used with variable success. We present a case of refractory stiff-man syndrome, in which the symptoms were successfully controlled by the administration of intravenous immunoglobulin (IVIg). This case gives evidence that IVIg can be a safe and an efficient treatment of refractory stiff-man syndrome. The exact indication for and the cost-effectiveness of IVIg in the treatment of this rare entity remain to be determined. |
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Authors:
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H Khanlou; G Eiger |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Mayo Clinic proceedings. Mayo Clinic Volume: 74 ISSN: 0025-6196 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 1999 Dec |
Date Detail:
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Created Date: 1999-12-29 Completed Date: 1999-12-29 Revised Date: 2007-10-29 |
Medline Journal Info:
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Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1231-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Albert Einstein Medical Center, Philadelphia, PA 19141, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Glutamate Decarboxylase / immunology* Humans Immunoglobulins, Intravenous / therapeutic use* Male Stiff-Person Syndrome / drug therapy*, enzymology, immunology* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous; EC 4.1.1.15/Glutamate Decarboxylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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