| Long-term prognostic value of dobutamine stress echocardiography in patients with atrial fibrillation. | |
| | |
MedLine Citation:
|
PMID: 11157596 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
STUDY OBJECTIVE: To assess the long-term prognostic value of dobutamine stress echocardiography (DSE) for cardiac events (cardiac death, myocardial infarction, and late revascularization) in patients with atrial fibrillation (AF). METHODS: Baseline ECGs were studied in patients undergoing DSE between 1989 and 1998. Sixty-nine patients had AF before DSE. Prognostic value of DSE in these patients was compared with a control group who had sinus rhythm (n = 1,664). The presence of stress-induced ischemia was noted for every patient. The mean follow-up period was 35 months (range, 6 to 84 months). Data are presented as hazards ratio (HR) with 95% confidence interval (CI). RESULTS: Heart rate at rest was higher in patients with AF (77 +/- 15 beats/min vs 73 +/- 14 beats/min; p = 0.04); however, double product at peak stress was not different between patients with AF and sinus rhythm (17,602 vs 17,169, respectively; p = 0.46). In patients with AF, target heart rate was achieved at a lower dobutamine dose (33 +/- 8 microg/kg/min vs 35 +/- 9 microg/kg/min; p = 0.01). Cardiac arrhythmias occurred more frequently (12% vs 5%; p = 0.001) in patients with AF during DSE. During a follow-up period of 7 years, cardiac death occurred in 5 patients, myocardial infarction in 2 patients, and late revascularization in 10 patients. Prognostic value of DSE for all late cardiac events was similar in patients with AF (HR, 3.0; 95% CI, 0.9 to 9.5) and sinus rhythm (HR, 3.4; 95% CI, 2.7 to 4.3; p = 0.85). CONCLUSION: The prognostic value of DSE for late cardiac events is maintained in patients with AF. |
| | |
Authors:
|
D Poldermans; J J Bax; A Elhendy; F Sozzi; E Boersma; I R Thomson; L J Jordaens |
Related Documents
:
|
7598296 - Effects of naloxone infusions in patients with the pruritus of cholestasis. a double-bl... 19904256 - Atrial fibrillation in end-stage renal disease: an emerging problem. 19368586 - Prevalence of fever in patients undergoing left atrial ablation of atrial fibrillation ... 17027826 - Left ventricular hypertrophy in patients with autonomic failure. 6785996 - Neurological complications in hemophilia. 2225886 - Community-acquired pneumonia: evidence of functional inactivation of alpha 1 proteinase... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Chest Volume: 119 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 2001 Jan |
Date Detail:
|
Created Date: 2001-02-22 Completed Date: 2001-03-22 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
|
Languages: eng Pagination: 144-9 Citation Subset: AIM; IM |
Affiliation:
|
Erasmus Medical Centre, Rotterdam, The Netherlands. poldermans@hlkd.azr.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Atrial Fibrillation / mortality, ultrasonography* Confidence Intervals Dobutamine / diagnostic use* Echocardiography* Exercise Test* Female Follow-Up Studies Humans Male Middle Aged Myocardial Infarction / mortality, ultrasonography Myocardial Revascularization Proportional Hazards Models Risk Factors Survival Rate |
| Chemical | |
Reg. No./Substance:
|
34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vascular endothelial growth factor in human lung transplantation.
Next Document: Left ventricular wall stress during leg-press exercise performed with a brief Valsalva maneuver.