| Long-term prognostic significance of three-dimensional echocardiographic parameters of the left ventricle and left atrium. | |
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MedLine Citation:
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PMID: 19995801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: We sought to investigate the long-term prognostic significance of two- and three-dimensional echocardiography. METHODS AND RESULTS: One hundred and seventy-eight consecutive outpatients underwent two-dimensional echocardiography and three-dimensional echocardiography for the assessment of LV volumes, mass, ejection fraction, and LA maximum and minimum volumes. After 45 months of follow-up, 31 patients (17%) had major cardiovascular events (death, myocardial infarctions, or stroke). From the two-dimensional echocardiography data, a significant time relationship to cardiovascular events was achieved only by LV end-systolic volume [hazard ratio (HR): 1.047; 95% confidence interval (CI): 0.994-1.083; P = 0.031] and mass (HR: 1.038; CI: 0.993-1.082; P = 0.019), whereas from three-dimensional echocardiography, all the examined variables: LV end-diastolic (HR: 1.014; CI: 1.003-1.025; P = 0.014) and end-systolic volume (HR:1.018; CI: 1.006-1.029; P = 0.003), ejection fraction (HR: 0.032; CI: 0.002-0.565; P = 0.019), mass (HR: 1.030; CI: 1.016-1.045; P < 0.001), LA maximum (HR: 1.055; CI: 1.031-1.080; P < 0.001) and minimum (HR: 1.049; CI: 1.028-1.070; P < 0.001) volumes, were found to bear a significant relationship to cardiovascular events. By multivariate analysis, three-dimensional echocardiography derived LA minimum volume was identified as the best independent predictor of adverse cardiovascular events (HR: 1.217; CI: 1.075-1.378; P = 0.002). CONCLUSION: Owing to a superior accuracy, three-dimensional echocardiography derived parameters and most notably LA minimum volume provide more relevant information on outpatient prognosis. |
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Authors:
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Stefano Caselli; Emanuele Canali; Maria Laura Foschi; Daria Santini; Emanuele Di Angelantonio; Natesa G Pandian; Stefano De Castro |
Publication Detail:
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Type: Journal Article Date: 2009-12-07 |
Journal Detail:
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Title: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology Volume: 11 ISSN: 1532-2114 ISO Abbreviation: Eur J Echocardiogr Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-08 Completed Date: 2010-11-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890618 Medline TA: Eur J Echocardiogr Country: England |
Other Details:
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Languages: eng Pagination: 250-6 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy. stefano.caselli@uniroma1.it |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiovascular Diseases / complications, mortality Echocardiography* Echocardiography, Three-Dimensional / methods Epidemiologic Factors Female Heart Atria / ultrasonography Heart Ventricles / ultrasonography Humans Male Middle Aged Outpatients Prognosis Stroke Volume / physiology Time Factors Ventricular Function, Left* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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