| Long-term prognosis of patients with variant angina. | |
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MedLine Citation:
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PMID: 3665004 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The long-term prognosis of variant angina and the factors influencing it were assessed in 217 consecutive patients hospitalized in our coronary care unit and followed for a mean of 65 months (range 2 to 123). Cardiac death occurred in 30 patients and an additional 54 experienced a nonfatal myocardial infarction. Survival at 1 and 5 years was 95% and 89%, respectively; survival without infarction was 83% and 69%. Coronary disease and the degree of disease activity were strong predictors of survival by Cox analysis. Survival at 1 year was 99%, and that at 5 years was 95% and 94%, respectively, for patients with one-vessel disease (n = 81) and for those without stenoses of 70% or greater (n = 87). Survival at 1 and 5 years was only 87% and 77% for those with multivessel disease (n = 40). The Cox analysis selected left ventricular function, initial treatment, extent score, duration of angina at rest, and disease activity as multivariate predictors of survival without infarction. Coronary disease was a strong predictor (p less than .0001) of survival without infarction by univariate analysis. Treatment with nifedipine, diltiazem, or verapamil improved survival without infarction compared with other medical treatment (p = .002). Myocardial infarction occurred most commonly soon after diagnosis in patients with a short history of angina at rest. Late coronary events were almost never preceded by resting angina. |
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Authors:
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A Walling; D D Waters; D D Miller; D Roy; G B Pelletier; P Théroux |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Circulation Volume: 76 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1987 Nov |
Date Detail:
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Created Date: 1987-12-10 Completed Date: 1987-12-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 990-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Montreal Heart Institute, Quebec, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris, Variant / diagnosis, mortality*, therapy Cause of Death Female Follow-Up Studies Heart Ventricles / physiopathology Humans Male Middle Aged Myocardial Infarction / mortality Prognosis Prospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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