Document Detail


Long-term prognosis of mitral-valve prolapse.
MedLine Citation:
PMID:  865549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We examined the natural history of mitral-valve prolapse in 53 patients who had had a midsystolic click or late systolic murmur (or both) documented phonocardiographically a mean of 13.7 years earlier. Thirty-eight patients were alive without serious complications, and seven had died of unrelated causes. In two patients prolapse was implicated in the cause of death. Other complications were ventricular fibrillation in one patient and bacterial endocarditis in three. Progressive mitral regurgitation developed in five patients, requiring valve replacement in two. These complications occurred in a total of eight patients (15 per cent), and were significantly (P = 0.15) associated with a late systolic murmur rather than an isolated midsystolic click. Thus it appears that the diagnosis of mitral-valve prolapse should not be regarded as ominous; however, patients in whom this diagnosis is associated with a late systolic murmur should be followed carefully.
Authors:
P Mills; J Rose; J Hollingsworth; I Amara; E Craige
Related Documents :
8452729 - Ct measurement of mediastinal anterior junction line in emphysema patients.
6463619 - Clinical findings and return to work after heart valve replacement.
16606389 - Transvenous pacemaker lead removal is safe and effective even in large vegetations: an ...
3518939 - Valvular heart disease in the elderly.
8280519 - Effect of aortic valve replacement on syncope in patients with aortic stenosis.
2670329 - Avoidance of embolic complications by ultrasonic characterization of the ascending aorta.
17966529 - Cmv colitis presenting as acute abdomen requires early diagnosis and treatment to avoid...
3977639 - Intracerebral hemorrhage with rapid recovery.
3262599 - Dissociation of visual deficits in ocular hypertension.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  297     ISSN:  0028-4793     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-07-29     Completed Date:  1977-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  13-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Echocardiography
Electrocardiography
Endocarditis, Bacterial / complications
Female
Follow-Up Studies
Heart Sounds
Humans
Male
Middle Aged
Mitral Valve Insufficiency / complications,  diagnosis,  mortality*
Phonocardiography
Prognosis
Time Factors
Ventricular Fibrillation / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Azorean disease of the nervous system.
Next Document:  The organization and structure of the national institutes of health.