Document Detail


Long-term prognosis of male patients with an isolated chronic occlusion of the left anterior descending coronary artery.
MedLine Citation:
PMID:  1957748     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to determine the long-term prognosis of patients with an isolated total occlusion of the left anterior descending artery (LAD). A total of 173 male patients with a chronic LAD occlusion and less than 50% narrowing of the other coronary arteries (group I) was compared with a group of 177 male patients with only insignificant coronary artery disease and a normal left ventricular function (group II). Baseline characteristics of both groups were comparable except for the inclusion of 54 patients (31.2%) with moderately or markedly reduced left ventricular systolic function in group I. During an 8-year follow-up period there was a greater number of patients with cardiac events in group I when compared with group II: cardiac death 11.2% versus 0.6% (p less than 0.0001), myocardial infarction 12.7% versus 3.4% (p = 0.001), myocardial revascularization procedures 11.6% versus 3.4% (p = 0.04). Stepwise discriminant analysis showed that a reduced ejection fraction and a family history of coronary artery disease were the best predictors for these adverse cardiac events.
Authors:
J Van Lierde; J Piessens; J J Glazier; M Vrolix; H De Geest; J L Willems
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  122     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1991-12-31     Completed Date:  1991-12-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1542-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, University Hospital Gasthuisberg, Leuven, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Belgium / epidemiology
Chronic Disease
Coronary Angiography
Coronary Disease / epidemiology,  mortality*,  radiography
Discriminant Analysis
Follow-Up Studies
Humans
Male
Myocardial Infarction / epidemiology,  mortality
Prognosis
Retrospective Studies
Risk Factors
Stroke Volume
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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