| Long-term prognosis for infants after massive fetomaternal hemorrhage. | |
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MedLine Citation:
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PMID: 17666598 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the fetal, neonatal, and long-term prognosis of massive fetomaternal hemorrhage (20 mL or more). METHODS: This series includes all patients with Kleihauer test values of 40 per 10,000 or higher over an 8-year period at two university hospitals. We examined obstetric, neonatal, and subsequent outcome data for the children. RESULTS: During the study period, 48 patients had massive fetomaternal hemorrhage (crude incidence 1.1 per 1,000; corrected incidence for Rh-negative women 4.6 per 1,000). Six fetal deaths were observed, representing 1.6% of all fetal deaths during the period. Nine newborns (18.7%) were transferred to neonatal intensive care unit (NICU) and five (10.4%) had transfusions. Fetomaternal hemorrhages of 20 mL/kg or more significantly increased the risk of fetal death, induced preterm delivery, transfer to NICU, and neonatal anemia requiring transfusion. Long-term follow-up was not associated with neurological sequelae (0%, 95% confidence interval 0.0-11.6%). CONCLUSION: When the transfused volume equals or exceeds 20 mL/kg, massive fetomaternal hemorrhage may lead to severe prenatal or neonatal complications. LEVEL OF EVIDENCE: III. |
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Authors:
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Chrystèle Rubod; Philippe Deruelle; Francoise Le Goueff; Virginie Tunez; Martine Fournier; Damien Subtil |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 110 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-08-01 Completed Date: 2007-08-30 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 256-60 Citation Subset: AIM; IM |
Affiliation:
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Hôpital Jeanne de Flandre, Université Lille II, 1 rue Eugène Avinée, 59037 Lille Cedex, France. c.rubod@orange.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anemia, Neonatal / blood, diagnosis Blood Transfusion Child Child, Preschool Female Fetal Death / etiology* Fetomaternal Transfusion / complications* Follow-Up Studies Humans Infant Infant, Newborn Pregnancy Prognosis Retrospective Studies |
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