Document Detail

Long-term prognosis in malignant or accelerated hypertension.
MedLine Citation:
PMID:  3132637     Owner:  NLM     Status:  MEDLINE    
In 51 consecutive patients with malignant hypertension collected from 1976 to 1981 we have analysed patient and kidney survival at 5 years and at last follow-up. The patients were 41 men, 10 women, mean age 53 years, with a stage III (63%) or stage IV (27%) fundi and a diastolic blood pressure (BP) greater than 130 mmHg. The hypertension was primary in 26, renovascular in 17 and secondary to bilateral nephropathy in eight. At 5-years follow-up, the patient and kidney survival rates were respectively 72.5% and 47%. At last follow-up, 18 patients had died (35%) and 18 additional patients require dialysis (renal death = 70%). The principal causes of death related to terminal renal failure and/or dialysis. Initial involvement of heart (27%) and brain (35%) led to a few more deaths. Blood pressure control reduced consequences for the heart and brain but not for the kidney. Patients at higher risk are those with serum creatinine greater than 200 mumol/l on admission.
C Guerin; R Gonthier; F C Berthoux
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  3     ISSN:  0931-0509     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  1988  
Date Detail:
Created Date:  1988-07-19     Completed Date:  1988-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  33-7     Citation Subset:  IM    
Faculté de Médecine, Hôpital Nord, Saint-Priest-en-Jarez, France.
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MeSH Terms
Blood Pressure
Creatinine / blood
Follow-Up Studies
Hypertension, Malignant / mortality*,  physiopathology
Kidney / physiology*
Middle Aged
Renal Dialysis
Reg. No./Substance:

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