Document Detail


Long-term peritoneal dialysis and encapsulating peritoneal sclerosis in children.
MedLine Citation:
PMID:  21476232     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Encapsulating peritoneal sclerosis (EPS) is the most serious complication of long-term peritoneal dialysis (PD), with a mortality rate that exceeds 30%. There have been many reports of the incidence of EPS being strongly correlated to the duration of PD. Patients on PD for longer than 5 years, and especially those receiving this treatment for more than 8 years, should undergo careful and repeated surveillance for risk factors associated with the development of EPS. The development of ultrafiltration failure, a high dialysate/plasma creatinine ratio, as determined by the peritoneal equilibration test, peritoneal calcification, a persistently elevated C-reactive protein level, and severe peritonitis in patients on PD for longer than 8 years are signals that should prompt the clinician to consider terminating PD as a possible means of preventing the development of EPS. The impact of the newer, biocompatible PD solutions on the incidence of EPS has not yet been determined.
Authors:
Masataka Honda; Bradley A Warady
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  25     ISSN:  1432-198X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2011-04-07     Completed Date:  2011-06-28     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  75-81     Citation Subset:  IM    
Affiliation:
Department of Pediatric Nephrology, Tokyo Metropolitan Children's Hospital, Umezono 1–3–1, Kiyoseshi, Tokyo 204-8567, Japan. masahonda@amy.hi-ho.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Humans
Japan / epidemiology
Peritoneal Dialysis / adverse effects*
Peritoneal Fibrosis / etiology*,  mortality,  prevention & control
Peritonitis / epidemiology,  etiology
Survival Rate
Withholding Treatment
Comments/Corrections

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