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Long-term peritoneal dialysis and encapsulating peritoneal sclerosis in children.
MedLine Citation:
PMID:  18853196     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Encapsulating peritoneal sclerosis (EPS) is the most serious complication of long-term peritoneal dialysis (PD), with a mortality rate that exceeds 30%. There have been many reports of the incidence of EPS being strongly correlated to the duration of PD. Patients on PD for longer than 5 years, and especially those receiving this treatment for more than 8 years, should undergo careful and repeated surveillance for risk factors associated with the development of EPS. The development of ultrafiltration failure, a high dialysate/plasma creatinine ratio, as determined by the peritoneal equilibration test, peritoneal calcification, a persistently elevated C-reactive protein level, and severe peritonitis in patients on PD for longer than 8 years are signals that should prompt the clinician to consider terminating PD as a possible means of preventing the development of EPS. The impact of the newer, biocompatible PD solutions on the incidence of EPS has not yet been determined.
Authors:
Masataka Honda; Bradley A Warady
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2008-10-14
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  -     ISSN:  1432-198X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pediatric Nephrology, Tokyo Metropolitan Children's Hospital, Umezono 1-3-1, Kiyoseshi, Tokyo, 204-8567, Japan, masahonda@amy.hi-ho.ne.jp.
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