Document Detail

Long-term outcomes of injection laryngoplasty in patients with potentially recoverable vocal fold paralysis.
MedLine Citation:
PMID:  20939083     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES/HYPOTHESIS: Injection laryngoplasty (IL) is a temporary intervention for unilateral vocal fold paralysis (UVFP). IL is often performed in patients with a potentially recoverable recurrent laryngeal nerve insult while awaiting spontaneous recovery, compensation, or definitive intervention. This study investigates the long-term outcomes of subjects treated with an IL.
STUDY DESIGN: Restrospective chart review.
METHODS: A single-institution, retrospective review was performed from January 2004 to July 2008; subjects with potentially recoverable UVFP who underwent an IL were included.
RESULTS: The following etiologies were noted for the 42 subjects included: idiopathic in 13 (31%), iatrogenic in 25 (60%), infectious in two (5%), traumatic in one (2%), and stroke in one (2%). Ten subjects (24%) had full recovery of their paralysis, four (10%) partially recovered movement with adequate recovery of voice, 16 (40%) had no recovery of motion but compensation with adequate recovery of voice, 12 (29%) required further definitive intervention in the form of laryngeal framework surgery. Voice-related quality of life scores improved for all patients surveyed after IL and improved more for those who ultimately recovered or compensated.
CONCLUSIONS: The majority of subjects with potentially recoverable UVFP recover vocal fold motion and/or adequate voice after IL without permanent intervention.
Lindsey C Arviso; Michael M Johns; Clyde C Mathison; Adam M Klein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  120     ISSN:  1531-4995     ISO Abbreviation:  Laryngoscope     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-29     Completed Date:  2011-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2237-40     Citation Subset:  IM    
Emory Voice Center, Atlanta, Georgia, USA.
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MeSH Terms
Carboxymethylcellulose Sodium / pharmacology
Cohort Studies
Collagen / pharmacology*
Follow-Up Studies
Hyaluronic Acid / pharmacology*
Injections, Intralesional
Laryngoscopy / methods
Middle Aged
Recovery of Function
Retrospective Studies
Severity of Illness Index
Time Factors
Treatment Outcome
Vocal Cord Paralysis / drug therapy*
Vocal Cords / drug effects
Voice Quality
Reg. No./Substance:
0/Alloderm; 9004-32-4/Carboxymethylcellulose Sodium; 9004-61-9/Hyaluronic Acid; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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