| Long-term outcomes of injection laryngoplasty in patients with potentially recoverable vocal fold paralysis. | |
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MedLine Citation:
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PMID: 20939083 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES/HYPOTHESIS: Injection laryngoplasty (IL) is a temporary intervention for unilateral vocal fold paralysis (UVFP). IL is often performed in patients with a potentially recoverable recurrent laryngeal nerve insult while awaiting spontaneous recovery, compensation, or definitive intervention. This study investigates the long-term outcomes of subjects treated with an IL. STUDY DESIGN: Restrospective chart review. METHODS: A single-institution, retrospective review was performed from January 2004 to July 2008; subjects with potentially recoverable UVFP who underwent an IL were included. RESULTS: The following etiologies were noted for the 42 subjects included: idiopathic in 13 (31%), iatrogenic in 25 (60%), infectious in two (5%), traumatic in one (2%), and stroke in one (2%). Ten subjects (24%) had full recovery of their paralysis, four (10%) partially recovered movement with adequate recovery of voice, 16 (40%) had no recovery of motion but compensation with adequate recovery of voice, 12 (29%) required further definitive intervention in the form of laryngeal framework surgery. Voice-related quality of life scores improved for all patients surveyed after IL and improved more for those who ultimately recovered or compensated. CONCLUSIONS: The majority of subjects with potentially recoverable UVFP recover vocal fold motion and/or adequate voice after IL without permanent intervention. |
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Authors:
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Lindsey C Arviso; Michael M Johns; Clyde C Mathison; Adam M Klein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Laryngoscope Volume: 120 ISSN: 1531-4995 ISO Abbreviation: Laryngoscope Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-29 Completed Date: 2011-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607378 Medline TA: Laryngoscope Country: United States |
Other Details:
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Languages: eng Pagination: 2237-40 Citation Subset: IM |
Affiliation:
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Emory Voice Center, Atlanta, Georgia, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carboxymethylcellulose Sodium / pharmacology Cohort Studies Collagen / pharmacology* Female Follow-Up Studies Humans Hyaluronic Acid / pharmacology* Injections, Intralesional Laryngoscopy / methods Male Middle Aged Recovery of Function Retrospective Studies Severity of Illness Index Time Factors Treatment Outcome Vocal Cord Paralysis / drug therapy* Vocal Cords / drug effects Voice Quality |
| Chemical | |
Reg. No./Substance:
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0/Alloderm; 9004-32-4/Carboxymethylcellulose Sodium; 9004-61-9/Hyaluronic Acid; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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