| Long-term outcomes in patients with atrioventricular block undergoing septal ventricular lead implantation compared with standard apical pacing. | |
| | |
MedLine Citation:
|
PMID: 18403387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: Left ventricular function may be altered by right ventricular apical pacing. The aims of the study were to compare the long-term course of different parameters of left ventricular dysfunction in patients undergoing implantation of a dual-chamber pacemaker with the ventricular lead in a septal position vs. in a standard apical position. METHODS: We randomized 98 patients with atrioventricular block (AV-block) undergoing pacemaker implantation to positioning the ventricular lead in the high or mid septum (n = 53) or in the apex (n = 45) of the right ventricle. N-terminal pro-brain natriuetic peptide (BNP) levels, left ventricular ejection fraction (LVEF), and exercise capacity were analysed 3 days, 3 months, and 18 months after the implantation. The primary endpoints were the changes of these parameters from baseline to 18 months. RESULTS: Changes of BNP levels, LVEF, and exercise capacity from baseline to 18 months were statistically not different between septal and apical stimulation. The clinical occurrence or deterioration of overt heart failure was similar in both treatment arms. CONCLUSION: With regard to different parameters of congestive heart failure, a septal stimulation site is not superior to conventional apical pacing in unselected patients undergoing pacemaker implantation for AV-block. |
| | |
Authors:
|
Alexander Kypta; Clemens Steinwender; Jürgen Kammler; Franz Leisch; Robert Hofmann |
Related Documents
:
|
18721597 - Thoracoscopic construction of an intrathoracic esophagogastric anastomosis using a circ... 11203637 - Changes in the masticatory function of complete denture wearers after relining the mand... 8472717 - Impaired subsidiary pacemaker function in patients with a right bundle branch block cre... 11028147 - Cardiac pacemakers. when clinical evaluation lags behind technological progress. 405017 - Acute myocardial infarction following gold sodium thiomalate induced vasomotor (nitrito... 21603067 - Bioenergetics, mitochondria, and cardiac myocyte differentiation. |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial Date: 2008-04-10 |
Journal Detail:
|
Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 10 ISSN: 1532-2092 ISO Abbreviation: Europace Publication Date: 2008 May |
Date Detail:
|
Created Date: 2008-04-29 Completed Date: 2008-05-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
|
Languages: eng Pagination: 574-9 Citation Subset: IM |
Affiliation:
|
First Department of Internal Medicine, Cardiovascular Division, Academic Teaching and General Hospital Linz, Krankenhausstrasse 9, A-4020 Linz, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Atrioventricular Block
/
diagnosis*,
prevention & control* Cardiac Pacing, Artificial / methods* Electrodes, Implanted* Female Heart Septum* Heart Ventricles* Humans Longitudinal Studies Male Prosthesis Implantation / methods* Treatment Outcome |
| Comments/Corrections | |
Comment In:
|
Europace. 2008 May;10(5):572-3
[PMID:
18403386
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Atrial fibrillation management by practice cardiologists: a prospective survey on the adherence to g...
Next Document: Verification of electrical isolation of pulmonary veins following left atrial circumferential ablati...