| Long-term outcomes of bifurcation lesions after implantation of drug-eluting stents with the "mini-crush technique". | |
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MedLine Citation:
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PMID: 17295334 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To evaluate clinical and angiographic long-term outcome of "the mini-crush" technique for treating bifurcation lesions. BACKGROUND: Despite proven efficacy of drug-eluting stent (DES) within most lesions subsets, bifurcation lesions continue to exhibit high restenosis rate using current DES stenting technique. METHODS: We report a new stenting technique which was employed in 45 consecutive patients (52 lesions) between April 2004 and July 2005 to treat true bifurcation lesions using DES in both branches. RESULTS: Using this technique procedural success was obtained in 100% of cases, without complications and with excellent angiographic result in 96.1% and 98.1% of main vessel and side branch. Preprocedure reference vessel diameter and minimal lumen diameter (MLD) were 2.68 +/- 0.48 and 0.90 +/- 0.55 mm for the main branch, respectively and 2.28 +/- 0.34 and 1.14 +/- 0.47 mm for the side branch, respectively. Postprocedure MLD was 2.56 +/- 0.39 mm for the main branch and 2.16 +/- 0.29 mm for the side branch. There were no in-hospital major adverse cardiac events (MACE). At 72 days after procedure there was one case of side branch stent thrombosis (2.2%), which resulted in non Q-wave MI. Angiographic follow up was obtained in 100% of patients at 7.5 +/- 1.3 months. Target lesion revascularization (TLR) was 12.2%; no death and Q-wave MI were observed; reference vessel diameter and MLD for the main branch were 2.79 +/- 0.51 and 1.99 +/- 0.65 mm respectively and for the side branch 2.28 +/- 0.40 and 1.63 +/- 0.48 mm respectively. Restenosis rate in the main branch was 12.2% while in the side branch was 2.0%. CONCLUSIONS: In-hospital outcome indicates that the mini-crush technique for bifurcation lesions with DES can be easily performed. It provides very low total MACE rate and restenosis at 8-month follow-up. These results confirmed the advantage of this specific technique to give complete coverage of the ostium of the side branch using two stents technique. |
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Authors:
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Alfredo R Galassi; Antonio Colombo; Maurice Buchbinder; Carmelo Grasso; Salvatore D Tomasello; Gian P Ussia; Corrado Tamburino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: 69 ISSN: 1522-1946 ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-05-31 Completed Date: 2007-07-13 Revised Date: 2008-05-29 |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 976-83 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine and Systemic Disease, Clinical Division of Cardiology, Ferrarotto Hospital, University of Catania, Italy. jimmanh2002@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary / adverse effects, methods* Cardiovascular Agents / administration & dosage, therapeutic use* Coronary Angiography Coronary Artery Disease / drug therapy, pathology, therapy* Coronary Restenosis / etiology, prevention & control Databases as Topic Female Follow-Up Studies Humans Male Middle Aged Myocardial Infarction / etiology, prevention & control Paclitaxel / administration & dosage, therapeutic use* Pilot Projects Prospective Studies Prosthesis Design Sirolimus / administration & dosage, therapeutic use* Stents* Thrombosis / complications, etiology, prevention & control Time Factors Treatment Outcome Ultrasonography, Interventional |
| Chemical | |
Reg. No./Substance:
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0/Cardiovascular Agents; 33069-62-4/Paclitaxel; 53123-88-9/Sirolimus |
| Comments/Corrections | |
Comment In:
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Catheter Cardiovasc Interv. 2008 May 1;71(6):E7-8
[PMID:
18412092
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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