Document Detail


Long-term outcomes after double-balloon enteroscopy for obscure gastrointestinal bleeding.
MedLine Citation:
PMID:  19514115     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND & AIMS: Long-term outcomes after doubleballoon enteroscopy (DBE), performed for the evaluation of obscure gastrointestinal bleeding, have not been determined. METHODS: We invited 274 patients undergoing DBE at Stanford University or the University of Chicago between 2004 and 2006 to participate in the study; 135 (49%) agreed (mean age, 64 +/- 14.8; range, 23-90 years). Telephone interviews were conducted at a mean of 11 and 30 months after DBE. RESULTS: Arteriovenous malformations (AVMs) were detected in 43% of the cohort. One hundred one patients (37%; 56 with overt, 45 with occult bleeding) were interviewed 12 +/- 5 (range, 6-26) months after DBE. At 12 months, 43% reported no further overt bleeding or iron/transfusion needs, 23% reported overt bleeding, and 35% reported ongoing iron and/or transfusions. Eighty-five patients (31%) participated in the second survey, conducted 30 +/- 5.7 (range, 19-51) months after DBE. Fifty (59%) reported no overt bleeding or iron/transfusion needs, 20 (24%) reported overt bleeding, and 15 (18%) reported ongoing iron and/or transfusions. In the 40 patients evaluated after endoscopic treatment for AVMs, 17 (43%) reported no bleeding or iron therapy at 12 months and 16 of 29 (55%) at 30 months. Of the 40 patients with normal DBE examinations to the depth of insertion, 19 of 40 (48%) reported no bleeding or iron/transfusion needs at 12 months and 25 of 43 (58%) at 30 months. CONCLUSIONS: At 30 months after DBE, up to 60% of patients report no further bleeding. Patients with AVMs or normal examinations to the depth of insertion are most likely to report recurrent hemorrhage.
Authors:
Lauren B Gerson; Melissa A Batenic; Sharese L Newsom; Andrew Ross; Carol E Semrad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association     Volume:  7     ISSN:  1542-7714     ISO Abbreviation:  Clin. Gastroenterol. Hepatol.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-09     Completed Date:  2009-07-27     Revised Date:  2009-10-22    
Medline Journal Info:
Nlm Unique ID:  101160775     Medline TA:  Clin Gastroenterol Hepatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  664-9     Citation Subset:  IM    
Affiliation:
Division of Gastroenterology and Hepatology, Stanford University, A149, 300 Pasteur Drive, Stanford, California 94305-5202, USA. lgerson@stanford.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Chicago
Endoscopy, Gastrointestinal / methods*
Female
Follow-Up Studies
Gastrointestinal Hemorrhage / diagnosis*,  therapy*
Humans
Interviews as Topic
Male
Middle Aged
Treatment Outcome
Young Adult
Comments/Corrections
Erratum In:
Clin Gastroenterol Hepatol. 2009 Sep;7(9):1019

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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