| Long-term outcomes after double-balloon enteroscopy for obscure gastrointestinal bleeding. | |
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MedLine Citation:
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PMID: 19514115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & AIMS: Long-term outcomes after doubleballoon enteroscopy (DBE), performed for the evaluation of obscure gastrointestinal bleeding, have not been determined. METHODS: We invited 274 patients undergoing DBE at Stanford University or the University of Chicago between 2004 and 2006 to participate in the study; 135 (49%) agreed (mean age, 64 +/- 14.8; range, 23-90 years). Telephone interviews were conducted at a mean of 11 and 30 months after DBE. RESULTS: Arteriovenous malformations (AVMs) were detected in 43% of the cohort. One hundred one patients (37%; 56 with overt, 45 with occult bleeding) were interviewed 12 +/- 5 (range, 6-26) months after DBE. At 12 months, 43% reported no further overt bleeding or iron/transfusion needs, 23% reported overt bleeding, and 35% reported ongoing iron and/or transfusions. Eighty-five patients (31%) participated in the second survey, conducted 30 +/- 5.7 (range, 19-51) months after DBE. Fifty (59%) reported no overt bleeding or iron/transfusion needs, 20 (24%) reported overt bleeding, and 15 (18%) reported ongoing iron and/or transfusions. In the 40 patients evaluated after endoscopic treatment for AVMs, 17 (43%) reported no bleeding or iron therapy at 12 months and 16 of 29 (55%) at 30 months. Of the 40 patients with normal DBE examinations to the depth of insertion, 19 of 40 (48%) reported no bleeding or iron/transfusion needs at 12 months and 25 of 43 (58%) at 30 months. CONCLUSIONS: At 30 months after DBE, up to 60% of patients report no further bleeding. Patients with AVMs or normal examinations to the depth of insertion are most likely to report recurrent hemorrhage. |
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Authors:
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Lauren B Gerson; Melissa A Batenic; Sharese L Newsom; Andrew Ross; Carol E Semrad |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Volume: 7 ISSN: 1542-7714 ISO Abbreviation: Clin. Gastroenterol. Hepatol. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-09 Completed Date: 2009-07-27 Revised Date: 2009-10-22 |
Medline Journal Info:
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Nlm Unique ID: 101160775 Medline TA: Clin Gastroenterol Hepatol Country: United States |
Other Details:
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Languages: eng Pagination: 664-9 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology and Hepatology, Stanford University, A149, 300 Pasteur Drive, Stanford, California 94305-5202, USA. lgerson@stanford.edu |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Chicago Endoscopy, Gastrointestinal / methods* Female Follow-Up Studies Gastrointestinal Hemorrhage / diagnosis*, therapy* Humans Interviews as Topic Male Middle Aged Treatment Outcome Young Adult |
| Comments/Corrections | |
Erratum In:
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Clin Gastroenterol Hepatol. 2009 Sep;7(9):1019 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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