Document Detail

Long-term outcome of percutaneous closure of secundum-type atrial septal defects in adults.
MedLine Citation:
PMID:  21044914     Owner:  NLM     Status:  In-Process    
AIMS: Transcatheter closure of the secundum-type atrial septal defect (ASD) is widely practised. We report complications and efficacy of percutaneous ASD closure in adults using the Amplatzer ASD occluder and the Cardioseal/Starflex device during long-term follow-up.
METHODS AND RESULTS: Between 1996 and 2008 percutaneous ASD closure was performed in 133 patients (mean age 46.8 ± 16.9 years; 36 men) by using the Amplatzer(r) device in 104 patients and the Cardioseal/Starflex device in 29. During a mean follow-up of 3.4 ± 2.8 years the occurrence of major complications was higher in patients with the Cardioseal/Starflex compared to patients with the Amplatzer(r) devices (17.2 vs. 2.9%, log rank, P=0.005), due to a higher embolisation rate (13.8 vs. 1.0%, log rank, P=0.002). In univariable analysis, the implantation of a Cardioseal/Starflex device (OR 6.0 (CI 1.4-25.2); P=0.01) and a larger device diameter (OR 1.1 (CI 1.0-1.2); P=0.04) were found to be predictors of the occurrence of major complications. Minor complications occurred in 10.5%, recurrent thrombo-embolism in 2.3% and residual shunting at six months was 13.9% without differences between devices. NYHA class improved from 1.8 ± 0.6 before to 1.2 ± 0.4 after closure (P<0.001) without differences between devices.
CONCLUSIONS: During long-term follow-up, percutaneous ASD closure in adults is safe and effective when using the Amplatzer(r) device. Larger Cardioseal/Starflex devices are related to a higher embolisation rate. Randomised trials are needed.
Justin G L M Luermans; Martijn C Post; Jurriën M ten Berg; H W Thijs Plokker; Maarten J Suttorp
Related Documents :
19796344 - Analysis of implantable defibrillator longevity under clinical circumstances: implicati...
2299084 - The modified fontan operation for children less than 4 years old.
15511244 - Long-term experience with subcutaneous icd leads: a comparison among three different ty...
11233394 - Improved early results with cavopulmonary connections.
21145054 - Single-balloon colonoscopy versus repeat standard colonoscopy for previous incomplete c...
24431854 - Presurgical orthopaedic nasoalveolar molding in cleft lip and palate infants: a compara...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  6     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  604-10     Citation Subset:  IM    
Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The cost effectiveness of primary angioplasty compared to thrombolysis in the real world: one year r...
Next Document:  Percutaneous coronary intervention in the elderly: results from the Thai National Percutaneous Coron...