| Long-term outcome following programmed electrical stimulation in patients with high-grade ventricular ectopy. | |
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MedLine Citation:
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PMID: 2456539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine if programmed electrical stimulation (PES) could be utilized to identify patients with high-grade ventricular ectopy at low- or high-risk for sudden cardiac death, we performed PES in 40 patients with high-grade ventricular ectopy refractory to conventional antiarrhythmic agents. Twenty-one patients had a previous myocardial infarction, five had cardiomyopathy, six had hypertension, three had valvular heart disease and five had no known structural heart disease. The mean age was 50 years (range, 18 to 76). During programmed ventricular stimulation, eight patients had inducible sustained (more than 30 seconds) monomorphic ventricular tachycardia (Group I) but in 32 patients sustained ventricular tachycardia was not inducible (Group II). None of the five patients without structural heart disease were inducible while seven out of 21 (33%) patients with previous myocardial infarction had inducible ventricular tachycardia (VT). Antiarrhythmic therapy was instituted in patients with inducible VT; patients without inducible VT did not receive antiarrhythmic agents. In Group I, seven of the eight patients are alive (mean follow-up, 16 months) and in Group II, 28 of the 32 patients are alive (mean follow-up, 17 months). None of the five deaths were sudden. We conclude that in the absence of antiarrhythmic therapy, the incidence of sudden cardiac death is very low in patients with high-grade ventricular ectopy who do not have inducible monomorphic ventricular tachycardia during programmed ventricular stimulation. |
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Authors:
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M H Kharsa; R L Gold; H Moore; Y Yazaki; C I Haffajee; J S Alpert |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 11 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1988 May |
Date Detail:
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Created Date: 1988-08-31 Completed Date: 1988-08-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 603-9 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Medicine, University of Massachusetts Medical Center, Worcester 01605. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Death, Sudden
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prevention & control* Electric Stimulation / methods* Female Follow-Up Studies Heart Ventricles Humans Male Tachycardia / mortality, physiopathology* Ventricular Fibrillation / mortality, physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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