Document Detail

Long-term outcome after pulmonary thromboendarterectomy.
MedLine Citation:
PMID:  10430723     Owner:  NLM     Status:  MEDLINE    
This study evaluated long-term outcome of pulmonary thromboendarterectomy (PTE) in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Survival, functional status, quality of life, health care utilization, and relationships between these parameters and postoperative pulmonary hemodynamics were assessed. Questionnaires were mailed to 420 patients who were more than 1 yr post-PTE; 308 responded (mean age, 56 yr [range, 19-89 yr]; mean years since PTE, 3.3 [range, 1- 16]). Survival after PTE was 75% at > 6 yr. After surgery, symptoms were markedly reduced. Median distance walked was 5,280 ft; 56 patients could walk "indefinitely." Of the working population, 62% of patients unemployed before PTE returned to work. Post-PTE patients scored several quality of life components of the Rand SF-36 slightly lower than reported normals but significantly higher than did pre-PTE patients. Ten percent of patients used oxygen. Ninety-three percent were in NYHA Class I or II. Disease-related hospitalizations/ER visits were minimal. A relationship was shown between 48 h postoperative pulmonary vascular resistance (PVR) and walking and stair-climbing ability, NYHA class, dyspnea scores, and the physical function and general health quality of life components. These data indicate that PTE offers most CTEPH patients substantial improvement in survival, function, and quality of life, with minimal disease-related health care utilization.
C J Archibald; W R Auger; P F Fedullo; R N Channick; K M Kerr; S W Jamieson; D P Kapelanski; C N Watt; K M Moser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of respiratory and critical care medicine     Volume:  160     ISSN:  1073-449X     ISO Abbreviation:  Am. J. Respir. Crit. Care Med.     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-08-30     Completed Date:  1999-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421642     Medline TA:  Am J Respir Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  523-8     Citation Subset:  AIM; IM    
Division of Pulmonary and Critical Care Medicine and Division of Cardiothoracic Surgery, University of California, San Diego, San Diego, California, USA.
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MeSH Terms
Activities of Daily Living / classification
Aged, 80 and over
Follow-Up Studies
Hypertension, Pulmonary / mortality,  surgery*
Middle Aged
Patient Readmission
Postoperative Complications / etiology*,  mortality
Pulmonary Embolism / mortality,  surgery*
Pulmonary Wedge Pressure
Quality of Life
Survival Rate
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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