| Long-term outcome of acute spinal cord ischemia syndrome. | |
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MedLine Citation:
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PMID: 14726546 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Current knowledge of long-term outcome in patients with acute spinal cord ischemia syndrome (ASCIS) is based on few studies with small sample sizes and <2 years' follow-up. Therefore, we analyzed clinical features and outcome of all types of ASCIS to define predictors of recovery. METHODS: From January 1990 through October 2002, 57 patients with ASCIS were admitted to our center. Follow-up data were available for 54. Neurological syndrome and initial degree of impairment were defined according to American Spinal Injury Association (ASIA)/International Medical Society of Paraplegia criteria. Functional outcome was assessed by walking ability and bladder control. RESULTS: Mean age was 59.4 years; 29 were women; and mean follow-up was 4.5 years. The origin was atherosclerosis in 33.3%, aortic pathology in 15.8%, degenerative spine disease in 15.8%, cardiac embolism in 3.5%, systemic hypotension in 1.8%, epidural anesthesia in 1.8%, and cryptogenic in 28%. The initial motor deficit was severe in 30% (ASIA grades A and B), moderate in 28% (ASIA C), and mild in 42% (ASIA D). At follow-up, 41% had regained full walking ability, 30% were able to walk with aids, 20% were wheelchair bound, and 9% had died. Severe initial impairment (ASIA A and B) and female sex were independent predictors of unfavorable outcome (P=0.012 and P=0.043). CONCLUSIONS: Considering a broad spectrum of clinical presentations and origins, the outcome in our study was more favorable than in previous studies reporting on ASCIS subgroups with more severe initial deficits. |
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Authors:
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Krassen Nedeltchev; Thomas J Loher; Frank Stepper; Marcel Arnold; Gerhard Schroth; Heinrich P Mattle; Matthias Sturzenegger |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2004-01-15 |
Journal Detail:
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Title: Stroke; a journal of cerebral circulation Volume: 35 ISSN: 1524-4628 ISO Abbreviation: Stroke Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-02-03 Completed Date: 2004-04-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0235266 Medline TA: Stroke Country: United States |
Other Details:
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Languages: eng Pagination: 560-5 Citation Subset: IM |
Affiliation:
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Department of Neurology, University Hospital of Bern, Inselspital, Bern, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Disability Evaluation Female Follow-Up Studies Gait Disorders, Neurologic / etiology Humans Magnetic Resonance Imaging Male Middle Aged Neurologic Examination Outcome Assessment (Health Care) / statistics & numerical data* Prognosis Recovery of Function Risk Factors Severity of Illness Index Sex Factors Spinal Cord Ischemia / complications, diagnosis*, physiopathology* Switzerland Syndrome Time Urinary Bladder, Neurogenic / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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