Document Detail

Long-term neurodevelopmental outcome after intrauterine laser treatment for severe twin-twin transfusion syndrome.
MedLine Citation:
PMID:  12712079     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to investigate long-term neurodevelopmental outcome after intrauterine laser treatment for twin-twin transfusion syndrome. STUDY DESIGN: All 89 surviving infants who were treated between January 1995 and May 1997 were investigated in a single center. Seventy-five children were tested with the Griffiths' Developmental Test Scales at a median age of 21 months; 14 children (median age, 34 months) were tested with the Snijders-Oomen-Non-Verbal-Intelligence Test. All children underwent a detailed standardized physical and neurologic examination. RESULTS: Sixty-nine infants (78%) showed a normal development (group I), 10 infants (11%) had minor neurologic deficiencies (group II), and 10 infants (11%) had major neurologic deficiencies (group III). No difference between recipient and donor status was observed (P =.93). There was a trend toward a more favorable outcome for those infants who were born as twins (53 infants [81%] in group I and 5 infants [8%] in group III) compared with singleton survivors after intrauterine death of the cotwin (16 infants [67%] in group I and 5 infants [21%] in group III); however, the difference was not significant (P =.12). CONCLUSION: After intrauterine laser treatment for twin-twin transfusion syndrome, 78% of the children had a normal neurodevelopmental status, 11% of the children had minor neurologic deficiencies, and 11% of the children had major neurologic deficiencies, at a median age of 22 months.
Corinna S Banek; Kurt Hecher; Bernhard J Hackeloer; Peter Bartmann
Related Documents :
8271129 - Development of lipolytic activity in gastric aspirates from premature infants.
18295169 - Heritability of parturition timing: an extended twin design analysis.
16009639 - Birth order and delivery interval: analysis of twin pair perinatal outcomes.
10096919 - Quenching of chlorophyll fluorescence by triplets in solubilized light-harvesting compl...
6538639 - Increased deaths due to endocrine system diseases and allergies among mothers of dizygo...
9499 - The significance of the time interval in twin delivery.
21385639 - Maternal child-feeding style during the weaning period: association with infant weight ...
23861689 - Maternal bmi, igf-i levels, and birth weight in african american and white infants.
7093619 - Season of birth in high and low genetic risk schizophrenics.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  188     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-24     Completed Date:  2003-05-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  876-80     Citation Subset:  AIM; IM    
Department of Neonatology, University Children's Hospital, Bonn, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Child Development*
Child, Preschool
Fetal Death / complications
Fetofetal Transfusion / complications*,  surgery*
Laser Coagulation*
Longitudinal Studies
Nervous System / growth & development*
Nervous System Diseases / etiology*,  physiopathology
Severity of Illness Index
Comment In:
Am J Obstet Gynecol. 2004 Apr;190(4):1170-1; author reply 1171-2   [PMID:  15132156 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Chorioamnionitis and increased neonatal lung lavage fluid matrix metalloproteinase-9 levels: implica...
Next Document:  Substance use and psychotherapeutic medications: a likely contributor to menstrual disorders in wome...