Document Detail


Long-term management of abetalipoproteinaemia. Possible role for vitamin E.
MedLine Citation:
PMID:  848999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight patients with abetalipoproteinaemia have been followed for 3-4 to 15-8 years. Management included dietary fat restriction and supplements of the fat-solublevitamins A, E, and K. In the 3 oldest patients serial studies of retinal and neurological function suggest that treatment with large doses of oral vitamin E may have delayed the development or progression of the neurological and retinal lesions.
Authors:
D P Muller; J K Lloyd; A C Bird
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  52     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-05-25     Completed Date:  1977-05-25     Revised Date:  2010-09-03    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  209-14     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abetalipoproteinemia / complications,  drug therapy*
Child
Female
Follow-Up Studies
Growth
Humans
Infant
Male
Neurologic Manifestations / etiology
Retinal Degeneration / etiology
Vitamin A / therapeutic use
Vitamin E / therapeutic use*
Chemical
Reg. No./Substance:
11103-57-4/Vitamin A; 1406-18-4/Vitamin E
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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