Document Detail

Long-term invasive measurement of subcutaneous oxygen partial pressure above the sacrum on lying healthy volunteers.
MedLine Citation:
PMID:  17014665     Owner:  NLM     Status:  MEDLINE    
Pressure ulcers are frequently seen dermal lesions, but little is known about their pathophysiology. It is generally assumed that prolonged tissue pressure impairs blood circulation thus causing ischemic damage to tissue. Therefore, subcutaneous oxygen partial pressure was measured to confirm this hypothesis. In the past, various authors have conducted tests on healthy subjects to determine oxygen partial pressure transcutaneously during periods not exceeding 20 minutes. All found a decrease at susceptible sites, e.g., the sacrum. The present study was the first one to measure oxygen partial pressure subcutaneously above the sacrums of four test subjects during a period of 5 hours. In all cases, the values first decreased to a minimum of 37% of baseline before they returned to the initial values. This observation is in contradiction to former studies, which start from the assumption of critical ischemia due to interface pressure, measured on healthy volunteers too.
Hans-Ullrich Völker; Gerhard Röper; Jürgen Sterk; Christian Willy
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society     Volume:  14     ISSN:  1067-1927     ISO Abbreviation:  Wound Repair Regen     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-10-03     Completed Date:  2007-02-08     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9310939     Medline TA:  Wound Repair Regen     Country:  United States    
Other Details:
Languages:  eng     Pagination:  542-7     Citation Subset:  IM    
Department of Pathology, Military Hospital, Ulm, Germany.
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MeSH Terms
Oxygen / analysis*
Partial Pressure
Pilot Projects
Pressure Ulcer / physiopathology
Sacrococcygeal Region*
Skin Physiological Phenomena
Supine Position
Reg. No./Substance:

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