Document Detail

Long-term impact of bronchopulmonary dysplasia on pulmonary function.
MedLine Citation:
PMID:  21969927     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Bronchopulmonary dysplasia (BPD) and the longterm respiratory consequences of prematurity are unfamiliar to adult respirologists and remain under-recognized entities to adult caregivers. In Canada, the incidence of preterm births and its main chronic respiratory complication, BPD, have increased over the past 25 years.
OBJECTIVE: To describe the posthospitalization morbidity, medication use, health care use and pulmonary function tests of a large cohort of individuals with preterm birth complicated by BPD.
METHODS: A retrospective review of the hospital records of 322 preterm infants with BPD was conducted. Outcome variables were compared across levels of disease severity. Differences between groups were tested with one-way ANOVA for continuous variables and the Mantel-Haenszel chi-squared test for ordinal variables.
RESULTS: Outcomes after the initial hospitalization that were associated with the initial severity of BPD were as follows: hospital readmissions in the first two years of life, the presence of developmental delay, forced expiratory volume in 1 s and forced vital capacity on pulmonary function tests in patients between eight and 15 years of age.
CONCLUSION: Initial BPD severity was an important predictor of pulmonary function abnormality and health care use during childhood.
Jennifer S Landry; Tiffany Chan; Larry Lands; Dick Menzies
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian respiratory journal : journal of the Canadian Thoracic Society     Volume:  18     ISSN:  1916-7245     ISO Abbreviation:  Can. Respir. J.     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-10-04     Completed Date:  2012-05-29     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  9433332     Medline TA:  Can Respir J     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  265-70     Citation Subset:  IM    
Respiratory Epidemiology & Clinical Research Unit, McGill University, Montreal, Quebec.
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MeSH Terms
Attention Deficit Disorder with Hyperactivity / epidemiology
Bronchopulmonary Dysplasia / complications,  epidemiology,  physiopathology*
Developmental Disabilities / epidemiology
Follow-Up Studies
Hearing Disorders / epidemiology
Infant, Newborn
Infant, Premature
Lung / physiopathology*
Nervous System Diseases / epidemiology
Respiratory Function Tests
Retrospective Studies
Severity of Illness Index
Vision, Low / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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