Document Detail


Long-term followup of all patients with muscle invasive (stages T2, T3 and T4) bladder carcinoma in a geographical region.
MedLine Citation:
PMID:  9224309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: We studied the relationship between long-term survival and treatment of stages T2, T3 and T4 bladder carcinoma in an unselected patient population. MATERIALS AND METHODS: A total of 680 patients with the initial diagnosis of bladder carcinoma in 1987 to 1988 in Western Sweden was prospectively registered and followed until 1994. Of these patients 107 had stage T2 to T3 and 41 had stage T4 disease. RESULTS: Of the patients with stage T2 to T3 disease 30 (mean age 66) underwent radical cystectomy, 33 (mean age 75) full dose radiotherapy and 44 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). The 5-year crude survival rates were 33, 15 and 14%, respectively. Of the patients with stage T4 disease 6 (mean age 61) underwent radical cystectomy, 9 (mean age 73) full dose radiotherapy and 26 (mean age 81) nonradical therapy (mainly transurethral resection of the bladder). All except 1 patient died of disease within 4 years. CONCLUSIONS: More than 60% of the patients in the cohort were considered unsuitable for radical cystectomy and their survival was poor, whether treated with full dose radiotherapy or transurethral resection of the bladder alone.
Authors:
S Holmäng; H Hedelin; C Anderström; S L Johansson
Related Documents :
15947569 - Update on chemotherapy for advanced bladder cancer.
24309529 - New agents: great expectations not realized.
3006439 - Radical irradiation of t2 and t3 bladder carcinoma. a retrospective investigation.
19757199 - Clusterin as a diagnostic and prognostic marker for transitional cell carcinoma of the ...
1305679 - 13-cis-retinoic acid in chemoprevention of superficial bladder cancer. the national bla...
9240179 - Combined chemotherapy and radiation with selective organ preservation for muscle-invasi...
20668609 - Thymic seminoma.
20828739 - Predicting the prognosis of hepatocellular carcinoma using gene expression.
10367539 - Single agent 2',2'-difluorodeoxycytidine in the treatment of metastatic urothelial carc...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of urology     Volume:  158     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-08-15     Completed Date:  1997-08-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  389-92     Citation Subset:  AIM; IM    
Affiliation:
Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Follow-Up Studies
Humans
Middle Aged
Muscle Neoplasms / mortality*,  pathology*,  therapy
Neoplasm Invasiveness
Neoplasm Staging
Prospective Studies
Survival Rate
Sweden / epidemiology
Time Factors
Urinary Bladder Neoplasms / mortality*,  pathology*,  therapy
Comments/Corrections
Comment In:
J Urol. 1997 Aug;158(2):406-7   [PMID:  9224312 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prognostic value of Ki-67 for recurrence and progression of superficial bladder cancer.
Next Document:  Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases.