Document Detail

Long term follow up of untreated primary hyperparathyroidism.
MedLine Citation:
PMID:  6437508     Owner:  NLM     Status:  MEDLINE    
Fourteen patients with primary hyperparathyroidism and whose initial serum calcium concentrations were 2.75 mmol/l (11.0 mg/100 ml) or more were followed up for five to 23 years without operative treatment. One had osteitis fibrosa when seen and died with a fibrosarcoma 22 years later. The remaining 13 patients, who were followed up for a mean of 10 years, came to little obvious harm from not being operated on. Their serum calcium concentrations did not rise and there was no evidence of progressive renal impairment. In four patients who presented originally with renal calculi there were three further episodes of renal colic in 54 patient years of follow up. Conservative management of primary hyperparathyroidism is not an unreasonable option, and patients who do not have symptoms need not necessarily be pressed to accept surgery.
C R Paterson; J Burns; E Mowat
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal (Clinical research ed.)     Volume:  289     ISSN:  0267-0623     ISO Abbreviation:  Br Med J (Clin Res Ed)     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1984-12-27     Completed Date:  1984-12-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8302911     Medline TA:  Br Med J (Clin Res Ed)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1261-3     Citation Subset:  AIM; IM    
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MeSH Terms
Calcium / blood
Creatinine / blood
Follow-Up Studies
Hyperparathyroidism / blood,  complications*,  therapy
Middle Aged
Reg. No./Substance:
60-27-5/Creatinine; 7440-70-2/Calcium

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