Document Detail

Long-term follow-up study of clear cell papulosis.
MedLine Citation:
PMID:  20605258     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Clear cell papulosis (CCP) was described as a new entity in 1987. Since then, only case reports or small case series have appeared in the literature and the long-term outcome of CCP remains unknown. OBJECTIVES: The aim of this study was to review cases of CCP diagnosed at our institution and to investigate their outcome. METHODS: Nineteen patients given a diagnosis of CCP more than 6 years previously were identified. Their medical records and histopathologic findings were reviewed. RESULTS: With a median follow-up duration of 11.5 years, regression of skin lesions was observed in 85.7% of patients. Persistence of skin lesions 11.5 years after diagnosis was confirmed histopathologically in one case, with a reduction in clear cell density. LIMITATIONS: Retrospective nature of the study is a limitation. CONCLUSION: No treatment is necessary for CCP because the skin lesions are asymptomatic and most patients experience at least partial regression.
Fang-Wen Tseng; Tseng-Tong Kuo; Pei-Hsuan Lu; Heng-Leong Chan; Ming-Jing Chan; Rosaline Chung-Yee Hui
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Publication Detail:
Type:  Journal Article     Date:  2010-06-03
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  63     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-16     Completed Date:  2010-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  266-73     Citation Subset:  IM    
Copyright Information:
Copyright 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
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MeSH Terms
Carcinoembryonic Antigen / metabolism
Child, Preschool
Disease Progression
Follow-Up Studies
Hypopigmentation / metabolism,  pathology*
Mucin-1 / metabolism
Paget Disease Extramammary / pathology
Remission, Spontaneous
Retrospective Studies
Skin / metabolism,  pathology*
Skin Diseases, Papulosquamous / metabolism,  pathology*
Staining and Labeling
Time Factors
Reg. No./Substance:
0/Carcinoembryonic Antigen; 0/Mucin-1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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