| Long-term follow-up study of clear cell papulosis. | |
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MedLine Citation:
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PMID: 20605258 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Clear cell papulosis (CCP) was described as a new entity in 1987. Since then, only case reports or small case series have appeared in the literature and the long-term outcome of CCP remains unknown. OBJECTIVES: The aim of this study was to review cases of CCP diagnosed at our institution and to investigate their outcome. METHODS: Nineteen patients given a diagnosis of CCP more than 6 years previously were identified. Their medical records and histopathologic findings were reviewed. RESULTS: With a median follow-up duration of 11.5 years, regression of skin lesions was observed in 85.7% of patients. Persistence of skin lesions 11.5 years after diagnosis was confirmed histopathologically in one case, with a reduction in clear cell density. LIMITATIONS: Retrospective nature of the study is a limitation. CONCLUSION: No treatment is necessary for CCP because the skin lesions are asymptomatic and most patients experience at least partial regression. |
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Authors:
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Fang-Wen Tseng; Tseng-Tong Kuo; Pei-Hsuan Lu; Heng-Leong Chan; Ming-Jing Chan; Rosaline Chung-Yee Hui |
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Publication Detail:
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Type: Journal Article Date: 2010-06-03 |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 63 ISSN: 1097-6787 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-16 Completed Date: 2010-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 266-73 Citation Subset: IM |
Copyright Information:
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Copyright 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoembryonic Antigen
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metabolism Child, Preschool Disease Progression Female Follow-Up Studies Humans Hypopigmentation / metabolism, pathology* Immunohistochemistry Infant Male Mucin-1 / metabolism Paget Disease Extramammary / pathology Remission, Spontaneous Retrospective Studies Skin / metabolism, pathology* Skin Diseases, Papulosquamous / metabolism, pathology* Staining and Labeling Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Carcinoembryonic Antigen; 0/Mucin-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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