Document Detail


Long-term follow-up study of HTLV-I infection in bottle-fed children born to seropositive mothers.
MedLine Citation:
PMID:  12504602     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human T-lymphotropic virus Type-I (HTLV-I) infects children via mother's milk. Infection of Human T-lymphotropic virus Type-I (HTLV-I) was investigated by long-term follow-up surveys of modified milk-fed children. Our observations of modified milk-fed infants revealed that: 1 of 154 (0.6%) at year 1, 5 of 129 (3.9%) at 1.5 years, and 5 of 108 (4.6%) at year 2 were anti-HTLV-I antibody-positive. No infants or children became newly antibody-positive thereafter. Modified milk feeding could prevent the HTLV-I infection of infants from mothers in many cases, however the infants who had became anti-HTLV-I antibody-positive due to established infection by the age 2 remained positive at age 11-12 with persistent infections. Modified milk-fed infants who had been born from HTLV-I seropositive mothers did not show that they had complete protection from HTLV-I infection, but a low infection rate was seen, showing that modified milk feeding is useful to protect from HTLV-I infection.
Authors:
Y Ando; Y Matsumoto; S Nakano; K Saito; K Kakimoto; T Tanigawa; Y Ekuni; M Kawa; T Toyama
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of infection     Volume:  46     ISSN:  0163-4453     ISO Abbreviation:  J. Infect.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2002-12-30     Completed Date:  2003-06-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7908424     Medline TA:  J Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  9-11     Citation Subset:  IM    
Affiliation:
Wakayama Medical University, Kihoku Hospital, Obstetrics and Gynecology, Myoji 219, Katsuragi, Ito, Japan. SNC76080@nifty.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Bottle Feeding*
Child
Child, Preschool
Female
Follow-Up Studies
HTLV-I Antibodies / blood*
HTLV-I Infections / immunology*,  transmission*
Humans
Infant
Infectious Disease Transmission, Vertical*
Male
Milk*
Milk, Human / virology
Pregnancy
Chemical
Reg. No./Substance:
0/HTLV-I Antibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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