Document Detail

Long-term follow-up of seizures associated with cerebral arteriovenous malformations. Results of therapy.
MedLine Citation:
PMID:  3994565     Owner:  NLM     Status:  MEDLINE    
Of 115 patients with angiographically demonstrated cerebral arteriovenous malformations (AVMs), seizures occurred in 66 (57%), all of whom had supratentorial AVMs. Seizures were the initial manifestations in 36 patients. In 14 patients seizures developed within 30 days of hemorrhage or surgical resection; in 16 others seizures started within 0.5 to 16 years after hemorrhage or resection. Seizures were infrequent in the majority of patients; in only nine (16%) were they incapacitating. Among 46 patients observed from two to 36 years, 23 (50%) were seizure free for a minimum of two years at follow-up. Neurological deficits on examination and previous occurrence of hemorrhage did not adversely affect seizure control. No significant difference was found between the percentage of seizure-free patients in the medical and surgical groups at follow-up. Irrespective of treatment method, seizures starting within 30 days of hemorrhage or resection had the best prognosis.
M J Murphy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  42     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-05-24     Completed Date:  1985-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  477-9     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Follow-Up Studies
Intracranial Arteriovenous Malformations / complications*,  surgery
Middle Aged
Retrospective Studies
Seizures / complications*,  surgery

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