Document Detail

Long term follow up of patients with IgA nephropathy.
MedLine Citation:
PMID:  8164897     Owner:  NLM     Status:  MEDLINE    
AIM: To assess the long term outcome of patients with IgA nephropathy. METHOD: The outcome of 151 patients (120 male; mean age 32.5, median age 29.6, SD 15.4 years; 146 Caucasian) with biopsy-proven IgA nephropathy. The patients were enrolled between 30 April 1973 and 21 August 1992. RESULTS: Ninety-five (63%) of the patients presented with microscopic haematuria, with or without proteinuria and/or renal insufficiency. At presentation renal insufficiency was present in 34% and hypertension in 48% of patients. During a mean follow up period of 63.3 months (range 0-233 months) 12 patients have reached end stage renal failure, five have died of a nonrenal cause and 25 were lost to follow up. The actuarial renal survival rate was 92.6% at five years and 91.1% at both 10 and 15 years. A significantly poorer renal survival rate was seen in those patients with a plasma creatinine > or = 0.12 mmol/L, hypertension, a serum albumin of < 35 g/L, or a 24 hour urinary albumin excretion > or = 1.0 g at presentation, and this became apparent within the first few years of follow up. CONCLUSIONS: The long term outcome of IgA nephropathy is better than previously reported. Those patients with a poor prognosis can be identified with considerable certainty at presentation.
R R Bailey; K L Lynn; R A Robson; A H Smith; J E Wells
Related Documents :
23379927 - Two-year outcome with the aperfix system for acl reconstruction.
24618607 - Squamous neoplasia of the scrotum: a series of 29 cases.
24902917 - Saddle-nose deformity repair with microplate-adapted costal cartilage.
20872347 - Improvement of cytokine response and survival time by bioartificial kidney therapy in a...
2644897 - Current status of proximal gastric vagotomy.
14754977 - Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 t...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New Zealand medical journal     Volume:  107     ISSN:  0028-8446     ISO Abbreviation:  N. Z. Med. J.     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-05-20     Completed Date:  1994-05-20     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0401067     Medline TA:  N Z Med J     Country:  NEW ZEALAND    
Other Details:
Languages:  eng     Pagination:  142-4     Citation Subset:  IM    
Department of Nephrology, Christchurch Hospital.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Actuarial Analysis
Age Distribution
Age Factors
European Continental Ancestry Group
Follow-Up Studies
Glomerulonephritis, IGA / complications,  ethnology,  mortality*
Hematuria / etiology
Hypertension, Renal / etiology
Middle Aged
New Zealand / epidemiology
Oceanic Ancestry Group
Proteinuria / etiology
Sex Distribution
Survival Analysis
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A commentary on in vivo lead X-ray fluorescence with reference to the 1992 workshop.
Next Document:  A descriptive study of occupational skin disease.