Document Detail

Long-term follow-up of patients with persistent/recurrent, isolated haematuria: a Hungarian multicentre study.
MedLine Citation:
PMID:  2702099     Owner:  NLM     Status:  MEDLINE    
A retrospective multicentre study of 341 children with persistent/recurrent, isolated haematuria is described. The haematuria was isolated for at least 6 months at the beginning of observation. The duration of follow-up was 2-5 years in 201, 5-10 years in 119, 10-15 years in 19, and over 15 years in 2 cases. Of these patients 47.8% became symptom-free. In 18.4% the haematuria remained isolated; in 13.8% it was combined with proteinuria over 250 mg/day more than 2 years later. The occurrence of associated proteinuria increased progressively with time. It was 8.6% between the 3rd and 5th years, and 37.0% after the 5th year. Renal biopsy was performed because of the symptoms of glomerular disease in 47 cases at an average time of 12 months following the appearance of proteinuria. Proteinuria appeared after a 2-5, 5-10, 10-15 and more than 15 years follow-up period in 16, 23, 6, and 2 patients respectively; 14 of them had Alport's nephropathy. The percentage of more serious azotaemia was 1.7 (creatinine clearance: 10-50 ml/min per 1.73 m2) and 0.3 (creatinine clearance: less than 10 ml/min per 1.73 m2). Mortality was 0.58%. Most of the patients who developed severe azotaemia had persistent microscopic haematuria at the beginning. The prevalence of hypertension was only 1.2%. The time of its appearance was above 5 years in 2 and below 5 years in 2 cases. All these patients had chronic glomerulonephritis. The haematuria was associated with hypercalciuria in 19.9%. In 14.3% of the overall group of patients urolithiasis developed 2-15 years after onset. All of these had hypercalciuria.(ABSTRACT TRUNCATED AT 250 WORDS)
S Túri; M Visy; A Vissy; V Jászai; Z Czirbesz; I Haszon; Z Szelid; I Ferkis
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study    
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  3     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1990-11-15     Completed Date:  1990-11-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  235-9     Citation Subset:  IM    
Department of Paediatrics, Albert Szent-Györgyi Medical University, Szeged, Hungary.
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MeSH Terms
Child, Preschool
Follow-Up Studies
Glomerulonephritis / complications*
Hematuria / etiology,  pathology*
Kidney / pathology*
Nephritis, Hereditary / complications*
Proteinuria / etiology
Retrospective Studies
Comment In:
Pediatr Nephrol. 1989 Jul;3(3):240-1   [PMID:  2702100 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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