Document Detail


Long-term follow-up of macular translocation with 360 degrees retinotomy for exudative age-related macular degeneration.
MedLine Citation:
PMID:  17923545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess long-term functional and morphological changes after macular translocation in patients with exudative age-related macular degeneration. METHODS: Evaluation of a noncomparative cohort study of 90 patients with a follow-up of 14 to 79 months (mean, 38.2 months). RESULTS: Visual acuity increased by 3 or more lines in 15 patients, remained stable in 35 patients, and deteriorated in 40 patients at final examination. Pigment epithelium atrophy extending to the new fovea was detected in 44 patients; in 25 patients this new atrophy was associated with loss of visual function. CONCLUSIONS: Long-term follow-up of macular translocation with 360 degrees retinotomy showed stabilization or improvement in half of the patients. Progressive atrophy of the pigment epithelium represented one major limiting factor of the beneficial effect of the treatment. Macular translocation may be an option for cases of exudative age-related macular degeneration that are not eligible for or do not respond to alternative treatments.
Authors:
Sabine Aisenbrey; Karl Ulrich Bartz-Schmidt; Peter Walter; Ralf Dieter Hilgers; Helen Ayertey; Peter Szurman; Gabriele Thumann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  125     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-09     Completed Date:  2007-10-25     Revised Date:  2007-12-19    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1367-72     Citation Subset:  AIM; IM    
Affiliation:
Department of Ophthalmology, University of Tuebingen, Schleichstrasse 12-16, 72076 Tuebingen, Germany. sabine.aisenbrey@med.uni-tuebingen.de
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MeSH Terms
Descriptor/Qualifier:
Atrophy / pathology
Exudates and Transudates
Fluorescein Angiography
Follow-Up Studies
Humans
Intraoperative Complications
Macula Lutea / surgery,  transplantation*
Macular Degeneration / diagnosis,  physiopathology,  surgery*
Ophthalmologic Surgical Procedures*
Pigment Epithelium of Eye / pathology
Postoperative Complications
Prospective Studies
Treatment Outcome
Vision Disorders / physiopathology
Visual Acuity / physiology
Comments/Corrections
Erratum In:
Arch Ophthalmol. 2007 Dec;125(12):1646

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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