| Long-term follow-up of children after repair of atrial septal defects. | |
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MedLine Citation:
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PMID: 8124844 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: It is critical to repair atrial septal defects during childhood to minimize long-term morbidity and mortality. However, only a few studies have examined factors that predict a favorable outcome. OBJECTIVE: To examine prognostic variables in the repair of atrial septal defects. METHODS: Retrospective analysis of children who underwent repair of atrial septal defects between 1957 and 1981. RESULTS: There were 70 girls and 57 boys with a mean age of 9.3 years at the time of surgery (range 4 months to 20 years). The most common presenting symptoms were fatigue and dyspnea. Before surgery, 74% were in New York Heart Association functional class I, 70% had echocardiographic evidence of right ventricular hypertrophy, and 55% had cardiomegaly on chest radiographs. The average mean pulmonary arterial pressure was 17.1 mm Hg. The only factor significantly related to poor outcome was pulmonary hypertension. Age at surgery did not influence long-term results. Ninety-four percent of patients were in functional class I at follow-up. CONCLUSIONS: Repair of atrial septal defects is safe before age 21, but it should be done as early as possible in order to minimize the long-term complications of chronic left-to-right shunting. |
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Authors:
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J Mandelik; D S Moodie; R Sterba; D Murphy; E Rosenkranz; S Medendorp; A Kovaks |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cleveland Clinic journal of medicine Volume: 61 ISSN: 0891-1150 ISO Abbreviation: Cleve Clin J Med Publication Date: 1994 Jan-Feb |
Date Detail:
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Created Date: 1994-04-12 Completed Date: 1994-04-12 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8703441 Medline TA: Cleve Clin J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 29-33; quiz 80-2 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Cleveland Clinic Foundation, OH 44195. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Child Child, Preschool Female Follow-Up Studies Heart Septal Defects, Atrial / surgery* Humans Infant Male Retrospective Studies |
| Comments/Corrections | |
Comment In:
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Cleve Clin J Med. 1994 Nov-Dec;61(6):473
[PMID:
7828339
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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