Document Detail

Long-term follow-up of children after repair of atrial septal defects.
MedLine Citation:
PMID:  8124844     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: It is critical to repair atrial septal defects during childhood to minimize long-term morbidity and mortality. However, only a few studies have examined factors that predict a favorable outcome. OBJECTIVE: To examine prognostic variables in the repair of atrial septal defects. METHODS: Retrospective analysis of children who underwent repair of atrial septal defects between 1957 and 1981. RESULTS: There were 70 girls and 57 boys with a mean age of 9.3 years at the time of surgery (range 4 months to 20 years). The most common presenting symptoms were fatigue and dyspnea. Before surgery, 74% were in New York Heart Association functional class I, 70% had echocardiographic evidence of right ventricular hypertrophy, and 55% had cardiomegaly on chest radiographs. The average mean pulmonary arterial pressure was 17.1 mm Hg. The only factor significantly related to poor outcome was pulmonary hypertension. Age at surgery did not influence long-term results. Ninety-four percent of patients were in functional class I at follow-up. CONCLUSIONS: Repair of atrial septal defects is safe before age 21, but it should be done as early as possible in order to minimize the long-term complications of chronic left-to-right shunting.
J Mandelik; D S Moodie; R Sterba; D Murphy; E Rosenkranz; S Medendorp; A Kovaks
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cleveland Clinic journal of medicine     Volume:  61     ISSN:  0891-1150     ISO Abbreviation:  Cleve Clin J Med     Publication Date:    1994 Jan-Feb
Date Detail:
Created Date:  1994-04-12     Completed Date:  1994-04-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8703441     Medline TA:  Cleve Clin J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  29-33; quiz 80-2     Citation Subset:  IM    
Department of Pediatrics, Cleveland Clinic Foundation, OH 44195.
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MeSH Terms
Age Factors
Child, Preschool
Follow-Up Studies
Heart Septal Defects, Atrial / surgery*
Retrospective Studies
Comment In:
Cleve Clin J Med. 1994 Nov-Dec;61(6):473   [PMID:  7828339 ]

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