| Long-term follow-up after cervical cancer treatment and subsequent successful surrogate pregnancy. | |
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MedLine Citation:
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PMID: 19712562 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preservation of fertility is a major concern for premenopausal women after diagnosis of cervical cancer. Successful surrogate pregnancy after treatment for cervical cancer has very rarely been reported. In the present report, a case of successful surrogate pregnancy after radical hysterectomy, lymphadenectomy and ovarian transposition for cervical cancer, followed by radiation therapy, is presented. After stimulation of the transposed ovaries using the short gonadotrophin-releasing hormone (GnRH) analogue protocol, four oocytes were retrieved transabdominally from the genetic mother. IVF followed and two embryos were transferred to the surrogate mother, leading to an uneventful singleton pregnancy, and ultimately normal vaginal delivery of a healthy female infant at term. The unique aspect in this case is the long-lasting favourable outcome for both genetic mother and child, observed during 8.5 years of follow-up, the longest follow-up period reported to date in such cases. |
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Authors:
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T Agorastos; M Zafrakas; M Mastrominas |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 19 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-08-28 Completed Date: 2009-11-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
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Languages: eng Pagination: 250-1 Citation Subset: IM |
Affiliation:
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1st Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Greece. agorast@auth.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Follow-Up Studies Humans Pregnancy Pregnancy Outcome* Surrogate Mothers* Uterine Cervical Neoplasms / therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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