| Long-term follow-up after invasive approach of coronary artery disease in daily practice. | |
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MedLine Citation:
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PMID: 16243111 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To assess long-term survival in unselected patients with coronary artery disease in who an invasive approach is considered. METHODS: All patients with significant coronary artery disease who were presented for coronary revascularisation to two tertiary centres in 1992 were included. Follow-up data were collected in September 2002. Multivariate Cox' proportional-hazards regression analysis was applied to assess the independent relation between variables and 10-year survival. RESULTS: A total of 877 patients were included in this analysis. Mean age was 62 and the most common clinical diagnosis was chronic stable angina (60%). Diabetes was present in 12% of the patients. During the follow-up period, 233 patients (27%) died. Predictors of long-term survival were increasing age, diabetes, peripheral vascular disease and a decreased left ventricular function. Compared to medical treated patients, those treated with revascularisation (either by PCI or CABG) had a decreased long-term mortality (p<0.05). Of the patients with PCI 27% had died, compared to 24% in those who had CABG and 36% of those who were treated medically. However, after adjusting for differences in baseline variables, conservative treatment was no significant predictor of long-term mortality. After multivariable analyses, increasing age, decreased left ventricular function and diabetes were independent predictors of long-term mortality. CONCLUSIONS: In patients with coronary artery disease in whom an invasive approach is considered, increasing age, impaired left ventricular function and diabetes are the strongest predictors of long-term mortality. After adjustments for differences in baseline variables, invasive treatment is not associated with a lower long-term mortality. |
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Authors:
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Arno Breeman; Jorik Timmer; Jan Paul Ottervanger; Evelien Kolkman; Ed de Kluiver; Henk Rigter; Piet Boonstra; Felix Zijlstra |
Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study |
Journal Detail:
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Title: International journal of cardiology Volume: 105 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-10-24 Completed Date: 2006-01-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 186-91 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Isala Klinieken, Locatie Weezenlanden, Groot Wezenland 20, 8011 JW Zwolle, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Angiography Coronary Disease / mortality, radiography, surgery* Female Follow-Up Studies Humans Male Middle Aged Myocardial Revascularization* Netherlands / epidemiology Prognosis Proportional Hazards Models Retrospective Studies Survival Rate / trends Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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