| Long-term follow-up of adalimumab monotherapy for rheumatoid arthritis in Japanese patients: a report of six cases. | |
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MedLine Citation:
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PMID: 21243493 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We present six cases of patients with Japanese rheumatoid arthritis (RA) treated with a tumor necrosis factor (TNF)-alpha blocking agent, adalimumab as monotherapy for 220 weeks. All six patients were women, and the median age was 54.0 ± 7.07 years old. The median duration of the disease was 7.43 ± 11.1 years, and the median disease activity score (DAS28-CRP) was 5.35 ± 0.69. Three of six patients were able to continue to receive this treatment for 220 weeks successfully, and the DAS28-CRP decreased to 1.89 ± 0.75. Two patients withdrew because of lack of efficacy, and one patient withdrew because of adverse events (non-Hodgkin lymphoma). Adalimumab resulted in a sustained clinical response in RA patients during 220-week follow-up. |
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Authors:
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Kunihiro Ichinose; Tomoki Origuchi; Shin-Ya Kawashiri; Naoki Iwamoto; Keita Fujikawa; Toshiyuki Aramaki; Makoto Kamachi; Kazuhiko Arima; Mami Tamai; Hideki Nakamura; Hiroaki Ida; Atsushi Kawakami; Katsumi Eguchi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-18 |
Journal Detail:
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Title: Rheumatology international Volume: - ISSN: 1437-160X ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8206885 Medline TA: Rheumatol Int Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Rheumatology, Unit of Translational Medicine, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan, kunizo1234abcd@yahoo.co.jp. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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