Document Detail


Long-term follow-up of Ethibloc injection in aneurysmal bone cysts.
MedLine Citation:
PMID:  19657285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study is to assess the long-term results of Ethibloc injection in aneurysmal bone cysts (ABC). Thirty-three patients with ABC were treated with computed tomography-guided percutaneous injection of Ethibloc into the cyst cavity. Twenty-two patients had Ethibloc injection as primary treatment and 11 patients had presented to us with recurrence after previous procedures including steroid injection, bone marrow injection, curettage bone grafting and various other surgical procedures. The mean follow-up was 54 (22-90) months. Symptoms were relieved in all patients. Two patients were lost to follow-up. Eighteen (58%) of the 31 patients followed, had complete resolution of the lesion, 11 (35.5%) patients had partial healing (asymptomatic residual nonprogressive lytic areas). Two (6.5%) patients showed recurrence in the proximal humerus during the follow-up. They are under follow-up but asymptomatic and another two patients encountered more significant complications after the procedure. Ethibloc injection is a relatively simple, minimally invasive alternative procedure for the treatment of ABC, and makes open operation unnecessary by stopping the expansion of the cyst and inducing endosteal new bone formation. This technique may be used as the primary management of ABC's excluding spinal lesions as shown by our largest and longest follow-up study.
Authors:
Harvey L George; Puthanveettil Nithin Unnikrishnan; Neeraj K Garg; Jayanth Sundar Sampath; Alf Bass; Colin E Bruce
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics. Part B     Volume:  18     ISSN:  1473-5865     ISO Abbreviation:  J Pediatr Orthop B     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2011-01-10     Completed Date:  2011-05-19     Revised Date:  2012-09-17    
Medline Journal Info:
Nlm Unique ID:  9300904     Medline TA:  J Pediatr Orthop B     Country:  United States    
Other Details:
Languages:  eng     Pagination:  375-80     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics, Alder Hey Children's Hospital, Liverpool, UK. harveygeorge@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Bone Cysts, Aneurysmal / drug therapy*,  radiography
Child
Child, Preschool
Diatrizoate / administration & dosage,  therapeutic use*
Drug Combinations
Fatty Acids / administration & dosage,  therapeutic use*
Female
Follow-Up Studies
Humans
Injections, Intralesional
Male
Propylene Glycols / administration & dosage,  therapeutic use*
Radiography, Interventional
Recurrence / prevention & control
Sclerosing Solutions / administration & dosage,  therapeutic use*
Treatment Outcome
Zein / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
0/Drug Combinations; 0/Fatty Acids; 0/Propylene Glycols; 0/Sclerosing Solutions; 117-96-4/Diatrizoate; 9010-66-6/Zein; 91196-33-7/alcoholic prolamine solution

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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